| 词条 | Bephenium hydroxynaphthoate |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 459957208 | IUPAC_name = N-Benzyl-N,N-dimethyl-2-phenoxyethanaminium 3-hydroxynaphthalene-2-carboxylate | image = Bephenium hydroxynaphthoate.svg | drug_name = | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = Undefined | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Oral | bioavailability = <1% | protein_bound = | metabolism = | elimination_half-life = | excretion = Renal (negligible) | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 3818-50-6 | CAS_supplemental = {{CAS|7181-73-9}} (bephenium) | ATC_prefix = P02 | ATC_suffix = CX02 | PubChem = 54678490 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 18524 | UNII_Ref = {{fdacite|changed|FDA}} | UNII = 47RU9546DX | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1673148 | C=28 | H=29 | N=1 | O=4 | smiles = C[N+](C)(CCOc1ccccc1)Cc2ccccc2.c1ccc2cc(c(cc2c1)C(=O)[O-])O | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C17H22NO.C11H8O3/c1-18(2,15-16-9-5-3-6-10-16)13-14-19-17-11-7-4-8-12-17;12-10-6-8-4-2-1-3-7(8)5-9(10)11(13)14/h3-12H,13-15H2,1-2H3;1-6,12H,(H,13,14)/q+1;/p-1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = PMPQCPQAHTXCDK-UHFFFAOYSA-M }} Bephenium hydroxynaphthoate (INN, trade names Alcopara, Alcopar, Befenium, Debefenium, Francin, Nemex) is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.[1][2] It is formulated as a salt between the active pharmaceutical ingredient, bephenium, and 3-hydroxy-2-naphthoic acid. Bephenium is not FDA-approved and is not available in the United States.[3] References1. ^{{cite book |editor=Sweetman S |title=The complete drug reference |edition=36th |location=London |publisher=Pharmaceutical Press |year=2009 |pages=143 |isbn=978-0-85369-840-1}} {{Anthelmintics}}{{Nicotinic acetylcholine receptor modulators}}{{antiinfective-drug-stub}}2. ^{{cite journal |vauthors=Jayewardene G, Ismail MM, Wijayaratnam Y |title=Bephenium hydroxynaphthoate in treatment of ascariasis |journal=Br Med J |volume=2 |issue=5194 |pages=268–71 |date=July 1960 |pmid=14406934 |pmc=2097409 |doi=10.1136/bmj.2.5194.268}} 3. ^{{cite web |url=http://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540057/all/Bephenium_hydroxynaphthoate |title=Bephenium hydroxynaphthoate |author=Pham PA |date=March 19, 2009 |work=Point-of-Care Information Technology ABX Guide |publisher=Johns Hopkins University}} Retrieved on March 25, 2011. 5 : Antiparasitic agents|Quaternary ammonium compounds|Phenol ethers|Benzyl compounds|Nicotinic agonists |
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