| 词条 | Bolasterone |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = (7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-7,10,13,17-tetramethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one | image = Bolasterone.png | width = 215px | tradename = Myagen, Methosarb | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = By mouth | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|CAS}} | CAS_number = 1605-89-6 | CAS_supplemental = | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 102146 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 92280 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = T7ZM08F7FU | KEGG = | ChEBI = | ChEMBL = 259548 | synonyms = U-19763; NSC-66233; 7α,17α-Dimethyltestosterone; 7α,17α-Dimethylandrost-4-en-17β-ol-3-one | C=21 | H=32 | O=2 | molecular_weight = 316.485 g/mol | SMILES = O=C4\\C=C3/[C@]([C@H]2CC[C@]1([C@@H](CC[C@@]1(O)C)[C@@H]2[C@H](C)C3)C)(C)CC4 | StdInChI_Ref = | StdInChI = 1S/C21H32O2/c1-13-11-14-12-15(22)5-8-19(14,2)16-6-9-20(3)17(18(13)16)7-10-21(20,4)23/h12-13,16-18,23H,5-11H2,1-4H3/t13-,16+,17+,18-,19+,20+,21+/m1/s1 | StdInChIKey_Ref = | StdInChIKey = IVFYLRMMHVYGJH-VLOLGRDOSA-N }}Bolasterone ({{abbrlink|INN|International Nonproprietary Name}}, {{abbrlink|USAN|United States Adopted Name}}) (brand names Myagen, Methosarb; former developmental code name U-19763), also known as 7α,17α-dimethyltestosterone, is a 17α-alkylated androgen/anabolic steroid (AAS) which is used in veterinary medicine.[1][2] It has close structural similarity to testosterone (medication)|testosterone, and like methyltestosterone has a methyl group at C17α in order to increase oral bioavailability.[1] In addition, it is also 7α-methylated, similar to its 7β-methylated isomer calusterone.[1] The medication has a low to moderate ratio of anabolic to androgenic activity, similar to that of fluoxymesterone.[3] References1. ^1 2 {{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA646|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=646–}} {{Androgens and antiandrogens}}{{Androgen receptor modulators}}{{Steroid-stub}}{{Genito-urinary-drug-stub}}2. ^{{cite book|author1=I.K. Morton|author2=Judith M. Hall|title=Concise Dictionary of Pharmacological Agents: Properties and Synonyms|url=https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA52|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-94-011-4439-1|pages=52–}} 3. ^{{cite book|author=Charles D. Kochakian|title=Anabolic-Androgenic Steroids|url=https://books.google.com/books?id=3-LrCAAAQBAJ&pg=PA377|date=6 December 2012|publisher=Springer Science & Business Media|isbn=978-3-642-66353-6|pages=377,401}} 4 : Androgens and anabolic steroids|Androstanes|Hepatotoxins|World Anti-Doping Agency prohibited substances |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。