“Bone marrow-derived macrophage”的意思、由来-开放百科全书

词条

Bone marrow-derived macrophage

释义

References

Bone-marrow-derived macrophage (BMDM) refers to macrophage cells that are generated in a research laboratory from mammalian bone marrow cells. Undifferentiated bone marrow cells are cultured in the presence of macrophage colony-stimulating factor (M-CSF; CSF1).^[1] M-CSF is a cytokine that directs cell differentiation toward an M2 polarization. These cells are often used in immunology and cell biology research.^[2]

References

1. ^{{Cite journal|last=Weischenfeldt|first=Joachim|last2=Porse|first2=Bo|date=2008-12-01|title=Bone Marrow-Derived Macrophages (BMM): Isolation and Applications|url=http://cshprotocols.cshlp.org/content/2008/12/pdb.prot5080|journal=Cold Spring Harbor Protocols|language=en|volume=2008|issue=12|pages=pdb.prot5080|doi=10.1101/pdb.prot5080|issn=1940-3402|pmid=21356739}}
2. ^oshizawa, S., et al. "Legionella Pneumophila Evades Gamma Interferon-Mediated Growth Suppression through Interleukin-10 Induction in Bone Marrow-Derived Macrophages." Infection and Immunity 73.5 (2005): 2709-17.

1 : Immunology

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