| 词条 | Bopindolol |
| 释义 |
| Verifiedfields = changed | verifiedrevid = 459981210 | IUPAC_name = (RS)-1-(tert-butylamino)-3-[(2-methyl-1H-indol-4-yl)oxy]propan-2-yl benzoate | image = Bopindolol.png | tradename = | Drugs.com = {{drugs.com|international|bopindolol}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = Rx-only | routes_of_administration = Oral | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 69010-88-4 | ATC_prefix = C07 | ATC_suffix = AA17 | ATC_supplemental = | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 357995 | PubChem = 44112 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = DB08807 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 40146 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = KT304VZO57 | KEGG_Ref = {{keggcite|changed|kegg}} | KEGG = D07537 | chemical_formula = | C=23 | H=28 | N=2 | O=3 | molecular_weight = 380.48 g/mol | smiles = CC1=CC2=C(N1)C=CC=C2OCC(CNC(C)(C)C)OC(=O)C3=CC=CC=C3 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C23H28N2O3/c1-16-13-19-20(25-16)11-8-12-21(19)27-15-18(14-24-23(2,3)4)28-22(26)17-9-6-5-7-10-17/h5-13,18,24-25H,14-15H2,1-4H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = UUOJIACWOAYWEZ-UHFFFAOYSA-N }}Bopindolol (INN) is a beta blocker. It is an ester which acts as a prodrug for its active metabolite 4-(3-t-butylamino-2-hydroxypropoxy)-2-methylindole.[1] See also
References1. ^{{cite journal | title=Bopindolol: pharmacological basis and clinical implications | vauthors=Nagatomo T, Hosohata Y, Ohnuki T, Nakamura T, Hattori K, Suzuki J, Ishiguro M | journal=Cardiovasc Drug Rev. |date=Spring 2001 | volume=19 | issue=1 | pages=9–24 | doi=10.1111/j.1527-3466.2001.tb00180.x | pmid=11314603}} {{Beta blockers}}{{Amine-stub}}{{cardiovascular-drug-stub}} 7 : Beta blockers|Prodrugs|Benzoates|Amines|Phenol ethers|Indoles|Tert-butyl compounds |
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