| 释义 |
- References
Brown induration is fibrosis and hemosiderin pigmentation of the lungs due to long standing pulmonary congestion (chronic passive congestion).Occurs with mitral stenosis and left sided heart failure . Pathology .. The lung vessels are congested with blood and this leads to pulmonary edema when plasma escapes in alveolar spaces . Rupture of congested capillaries leads to release of hemosiderin from damaged Red Blood cells . When alveolar macrophages engulf hemosiderin they are called heart failure cells . Death of heart failure cells in their journey back to lung tissue with subsequent hemosiderin release leads to lung fibrosis .[1][2][3] References 1. ^Stedman's Medical Dictionary for the Health Professions and Nursing
2. ^Pathology 3rd edition, BRS series, Schneider et al
3. ^Idiopathic pulmonary haemosiderosis (essential brown induration of the lung), Wyllie, W.G et al
{{respiratory-disease-stub}} 1 : Lung disorders |