词条 | Butofilolol |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 477374938 | IUPAC_name = (RS)-1-[2-[3-(tert-butylamino)-2-hydroxypropoxy]-5-fluorophenyl]butan-1-one | image = Butofilolol skeletal.svg | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 64552-17-6 | CAS_supplemental = | ATC_prefix = none | ATC_suffix = | ATC_supplemental = | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 157443 | PubChem = 68838 | IUPHAR_ligand = | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 4AZC6Y5A8G | synonyms = CM-6805 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 62071 | chemical_formula = | C=17 | H=26 | F=1 | N=1 | O=3 | molecular_weight = 311.392 g/mol | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C17H26FNO3/c1-5-6-15(21)14-9-12(18)7-8-16(14)22-11-13(20)10-19-17(2,3)4/h7-9,13,19-20H,5-6,10-11H2,1-4H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = NMBNQRJDEPOXCP-UHFFFAOYSA-N | smiles = Fc1ccc(OCC(O)CNC(C)(C)C)c(c1)C(=O)CCC }} Butofilolol (trade name Cafide) is a beta-blocker drug for the treatment of essential hypertension (high blood pressure).[1][2] It is not known to be marketed anywhere. References1. ^{{Cite journal | last1 = Houin | first1 = G | last2 = Barre | first2 = J | last3 = Jeanniot | first3 = JP | last4 = Ledudal | first4 = P | last5 = Cautreels | first5 = W | last6 = Tillement | first6 = JP | title = Pharmacokinetics of butofilolol (CAFIDE) after repeated oral administration in man | journal = International Journal of Clinical Pharmacology Research | volume = 4 | issue = 3 | pages = 175–83 | year = 1984 | pmid = 6149195}} {{Adrenergics}}{{antihypertensive-stub}}2. ^{{Cite journal | last1 = Toussain | first1 = P | last2 = Gay | first2 = G | last3 = Debry | first3 = G | title = Long-term hypotensive treatment by butofilolol | journal = Annales de Cardiologie et d'Angeiologie | volume = 32 | issue = 4 | pages = 277–83 | year = 1983 | pmid = 6412614}} 1 : Beta blockers |
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