“Calumenin”的意思、由来-开放百科全书

Calumenin (CALU) is a calcium-binding protein localized in the endoplasmic reticulum (ER) and is involved in such ER functions as protein folding and sorting. Calumenin is a member of the EF-hand superfamily in the ER and Golgi apparatus named CERC. CERC is an acronym for its family members Cab-45, reticulocalbin, Erc-55 (RCN2), and calumenin. The CALU gene encodes a deduced 315-amino acid protein containing 6 EF-hand motifs, 1 potential N-glycosylation site, and a C-terminal ER retention signal. The human and mouse CALU proteins are 98% identical. CALU mRNA is ubiquitously expressed in human tissues and maps to 7q32.^[2]

References

1. ^{{cite journal | vauthors = Yabe D, Taniwaki M, Nakamura T, Kanazawa N, Tashiro K, Honjo T | title = Human calumenin gene (CALU): cDNA isolation and chromosomal mapping to 7q32 | journal = Genomics | volume = 49 | issue = 2 | pages = 331–3 |date=Aug 1998 | pmid = 9598325 | pmc = | doi = 10.1006/geno.1998.5245 }}
2. ^¹{{cite web | title = Entrez Gene: CALU calumenin| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=813| accessdate = }}

Further reading

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1 : EF-hand-containing proteins

References

External links

Further reading