| 释义 |
- Interactions
- References
- External links
- Further reading
{{Infobox_gene}}Cullin-associated NEDD8-dissociated protein 1 is a protein that in humans is encoded by the CAND1 gene.[1][2][3] Interactions CAND1 has been shown to interact with: {{div col|colwidth=20em}}- CUL1,[4][4]
- CUL2,[4][4]
- CUL3,[4]
- CUL4A,[5]
- CUL4B,[5]
- DCUN1D1,[11] and
- RBX1.[5][6]
{{Div col end}} References 1. ^{{cite journal | vauthors = Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Research | volume = 5 | issue = 6 | pages = 355–64 | date = Dec 1998 | pmid = 10048485 | pmc = | doi = 10.1093/dnares/5.6.355 }}
2. ^{{cite journal | vauthors = Yogosawa S, Makino Y, Yoshida T, Kishimoto T, Muramatsu M, Tamura T | title = Molecular cloning of a novel 120-kDa TBP-interacting protein | journal = Biochemical and Biophysical Research Communications | volume = 229 | issue = 2 | pages = 612–7 | date = Dec 1996 | pmid = 8954946 | pmc = | doi = 10.1006/bbrc.1996.1852 }}
3. ^{{cite web | title = Entrez Gene: CAND1 cullin-associated and neddylation-dissociated 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55832| accessdate = }}
4. ^1 {{cite journal | vauthors = Menon S, Tsuge T, Dohmae N, Takio K, Wei N | title = Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome | journal = BMC Biochemistry | volume = 9 | issue = | pages = 1 | pmid = 18173839 | pmc = 2265268 | doi = 10.1186/1471-2091-9-1 | year = 2008 }}
5. ^1 2 3 4 5 {{cite journal | vauthors = Min KW, Hwang JW, Lee JS, Park Y, Tamura TA, Yoon JB | title = TIP120A associates with cullins and modulates ubiquitin ligase activity | journal = The Journal of Biological Chemistry | volume = 278 | issue = 18 | pages = 15905–10 | date = May 2003 | pmid = 12609982 | doi = 10.1074/jbc.M213070200 }}
6. ^1 {{cite journal | vauthors = Kim AY, Bommeljé CC, Lee BE, Yonekawa Y, Choi L, Morris LG, Huang G, Kaufman A, Ryan RJ, Hao B, Ramanathan Y, Singh B | title = SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation | journal = The Journal of Biological Chemistry | volume = 283 | issue = 48 | pages = 33211–20 | date = Nov 2008 | pmid = 18826954 | pmc = 2586271 | doi = 10.1074/jbc.M804440200 }}
External links Further reading {{refbegin | 2}}- {{cite journal | vauthors = Yogosawa S, Kayukawa K, Kawata T, Makino Y, Inoue S, Okuda A, Muramatsu M, Tamura T | title = Induced expression, localization, and chromosome mapping of a gene for the TBP-interacting protein 120A | journal = Biochemical and Biophysical Research Communications | volume = 266 | issue = 1 | pages = 123–8 | date = Dec 1999 | pmid = 10581176 | doi = 10.1006/bbrc.1999.1773 }}
- {{cite journal | vauthors = Hu RM, Han ZG, Song HD, Peng YD, Huang QH, Ren SX, Gu YJ, Huang CH, Li YB, Jiang CL, Fu G, Zhang QH, Gu BW, Dai M, Mao YF, Gao GF, Rong R, Ye M, Zhou J, Xu SH, Gu J, Shi JX, Jin WR, Zhang CK, Wu TM, Huang GY, Chen Z, Chen MD, Chen JL | title = Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 97 | issue = 17 | pages = 9543–8 | date = Aug 2000 | pmid = 10931946 | pmc = 16901 | doi = 10.1073/pnas.160270997 }}
- {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Research | volume = 11 | issue = 3 | pages = 422–35 | date = Mar 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
- {{cite journal | vauthors = Liu J, Furukawa M, Matsumoto T, Xiong Y | title = NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases | journal = Molecular Cell | volume = 10 | issue = 6 | pages = 1511–8 | date = Dec 2002 | pmid = 12504025 | doi = 10.1016/S1097-2765(02)00783-9 }}
- {{cite journal | vauthors = Zheng J, Yang X, Harrell JM, Ryzhikov S, Shim EH, Lykke-Andersen K, Wei N, Sun H, Kobayashi R, Zhang H | title = CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex | journal = Molecular Cell | volume = 10 | issue = 6 | pages = 1519–26 | date = Dec 2002 | pmid = 12504026 | doi = 10.1016/S1097-2765(02)00784-0 }}
- {{cite journal | vauthors = Min KW, Hwang JW, Lee JS, Park Y, Tamura TA, Yoon JB | title = TIP120A associates with cullins and modulates ubiquitin ligase activity | journal = The Journal of Biological Chemistry | volume = 278 | issue = 18 | pages = 15905–10 | date = May 2003 | pmid = 12609982 | doi = 10.1074/jbc.M213070200 }}
- {{cite journal | vauthors = Feng S, Shen Y, Sullivan JA, Rubio V, Xiong Y, Sun TP, Deng XW | title = Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein Degradation | journal = The Plant Cell | volume = 16 | issue = 7 | pages = 1870–82 | date = Jul 2004 | pmid = 15208391 | pmc = 514167 | doi = 10.1105/tpc.021949 }}
- {{cite journal | vauthors = Goldenberg SJ, Cascio TC, Shumway SD, Garbutt KC, Liu J, Xiong Y, Zheng N | title = Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases | journal = Cell | volume = 119 | issue = 4 | pages = 517–28 | date = Nov 2004 | pmid = 15537541 | doi = 10.1016/j.cell.2004.10.019 }}
- {{cite journal | vauthors = Min KW, Kwon MJ, Park HS, Park Y, Yoon SK, Yoon JB | title = CAND1 enhances deneddylation of CUL1 by COP9 signalosome | journal = Biochemical and Biophysical Research Communications | volume = 334 | issue = 3 | pages = 867–74 | date = Sep 2005 | pmid = 16036220 | doi = 10.1016/j.bbrc.2005.06.188 }}
- {{cite journal | vauthors = Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, Wakamatsu A, Kimura K, Sakamoto K, Hatano N, Kawai Y, Ishii S, Saito K, Kojima S, Sugiyama T, Ono T, Okano K, Yoshikawa Y, Aotsuka S, Sasaki N, Hattori A, Okumura K, Nagai K, Sugano S, Isogai T | title = Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries | journal = DNA Research | volume = 12 | issue = 2 | pages = 117–26 | year = 2007 | pmid = 16303743 | doi = 10.1093/dnares/12.2.117 }}
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