| 词条 | Candicidin |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 460122980 | IUPAC_name = 33-[(3-Amino-3,6-dideoxy-D-mannopyranosyl)oxy]-17-[6-(4-aminophenyl)-4-hydroxy-1,3-dimethyl-6-oxohexyl]-1,3,5,7,37-pentahydroxy-18-methyl-9,13,15-trioxo-16,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid | image = Candicidin.png | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 1403-17-4 | ATC_prefix = G01 | ATC_suffix = AA04 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C59H84N2O18/c1-35-18-15-13-11-9-7-5-6-8-10-12-14-16-21-46(77-58-55(72)53(61)54(71)38(4)76-58)31-50-52(57(73)74)49(69)34-59(75,79-50)33-45(66)29-44(65)28-43(64)27-41(62)19-17-20-42(63)30-51(70)78-56(35)37(3)26-36(2)47(67)32-48(68)39-22-24-40(60)25-23-39/h5-16,18,21-25,35-38,43-47,49-50,52-56,58,64-67,69,71-72,75H,17,19-20,26-34,60-61H2,1-4H3,(H,73,74)/b6-5-,9-7-,10-8-,13-11-,14-12-,18-15-,21-16-/t35?,36?,37?,38-,43?,44?,45?,46?,47?,49?,50?,52?,53+,54-,55+,56?,58?,59?/m1/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = YKSVGLFNJPQDJE-WDANKXQLSA-N | PubChem = 441142 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = DB01152 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 10128184 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 48N2IYJ202 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1200647 | C=59 | H=84 | N=2 | O=18 | molecular_weight = 1109.32 g/mol | smiles = Nc1ccc(cc1)C(=O)CC(O)C(C)CC(C)C3OC(=O)CC(=O)CCCC(=O)CC(O)CC(O)CC(O)CC4(O)CC(O)C(C(=O)O)C(CC(OC2O[C@H](C)[C@@H](O)[C@H](N)[C@@H]2O)C=CC=CC=CC=CC=CC=CC=CC3C)O4 }}Candicidin is an antifungal compound obtained from Streptomyces griseus. It is active against some fungi including Candida albicans. Candicidin is administered intravaginally in the treatment of vulvovaginal candidiasis.[1] This bioactive compound was named candicidin, because of its high activity on Candida albicans.[2] References1. ^{{ cite web | title = Product information Candicidin | url = http://www.toku-e.com/Upload/Products/PDS/20120604006556.pdf | format = pdf | publisher = Toku-E | date = 2012-01-11 | accessdate = 2012-06-11 }} {{Gynecological anti-infectives and antiseptics}}{{genito-urinary-drug-stub}}2. ^Selman A. Waksman, Hubert A. Lechevalier & Carl P. Schaffner: Candicidin and other Polyenic Antifungal Antibiotics, 1965, 33, 219-226 3 : Macrolides|Antifungals|Polyenes |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。