| 词条 | Carfenazine |
| 释义 |
| IUPAC_name = 1-(103-[4-(2-Hydroxyethyl)piperazin-1-yl]propyl10H-phenothiazin-2-yl)propan-1-one | image = Carphenazine.svg | width = 250 | alt = | image2 = | width2 = | drug_name = | tradename = | licence_EU = | licence_US = Proketazine | DailyMedID = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = Withdrawn | dependency_liability = | routes_of_administration = Oral | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number = 2622-30-2 | CAS_supplemental = | ATCvet = | ATC_prefix = none | ATC_suffix = | ATC_supplemental = | PubChemSubstance = | IUPHAR_ligand = 7140 | DrugBank = DB01038 | PubChem = 18104 | ChemSpiderID = 17100 | synonyms = Proketazine, Carphenazin | chemical_formula = | C=24 | H=31 | N=3 | O=2 | S=1 | molecular_weight = 425.6 g/mol | SMILES = CCC(=O)c1ccc2Sc3ccccc3N(CCCN4CCN(CCO)CC4)c2c1 | StdInChI = 1S/C24H31N3O2S/c1-2-22(29)19-8-9-24-21(18-19)27(20-6-3-4-7-23(20)30-24)11-5-10-25-12-14-26(15-13-25)16-17-28/h3-4,6-9,18,28H,2,5,10-17H2,1H3 | StdInChIKey = XZSMZRXAEFNJCU-UHFFFAOYSA-N | UNII = CLY16Y8Z7E | ChEMBL = 1201328 | density = | melting_point = | melting_high = | melting_notes = | boiling_point = | boiling_notes = | solubility = | specific_rotation = | sec_combustion = }}Carfenazine (INN) (former developmental code name WY-2445), or carphenazine (BAN), also known as carphenazine maleate (USAN) (brand name Proketazine; former developmental code name NSC-71755), is an antipsychotic and tranquilizer of the phenothiazine group that was withdrawn from the market.[1][2][3] References1. ^{{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA224|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=224–}} {{Antipsychotics}}{{Adrenergics}}{{Cholinergics}}{{Dopaminergics}}{{Histaminergics}}{{Serotonergics}}{{Tricyclics}}{{nervous-system-drug-stub}}2. ^{{cite book|author=William Andrew Publishing|title=Pharmaceutical Manufacturing Encyclopedia, 3rd Edition|url=https://books.google.com/books?id=_J2ti4EkYpkC&pg=PA862|date=22 October 2013|publisher=Elsevier|isbn=978-0-8155-1856-3|pages=862–}} 3. ^{{cite book|author1=Gerald G. Briggs|author2=Roger K. Freeman|author3=Sumner J. Yaffe|title=Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk|url=https://books.google.com/books?id=OIgTE4aynrMC&pg=PA213|year=2011|publisher=Lippincott Williams & Wilkins|isbn=978-1-60831-708-0|pages=213–}} 3 : Phenothiazines|Typical antipsychotics|Withdrawn drugs |
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