| 词条 | CCPA (biochemistry) |
| 释义 |
| verifiedrevid = 403603722 | Name = CCPA | ImageFile = 2-Chloro-N(6)cyclopentyladenosine.svg | ImageSize = 250px | IUPACName = (2R,3R,4S,5R)-2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl) oxolane-3,4-diol | SystematicName = | OtherNames = |Section1={{Chembox Identifiers | Abbreviations = CCPA | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 110356 | InChIKey = XSMYYYQVWPZWIZ-IDTAVKCVBF | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C15H20ClN5O4/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(24)10(23)8(5-22)25-14/h6-8,10-11,14,22-24H,1-5H2,(H,18,19,20)/t8-,10-,11-,14-/m1/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = XSMYYYQVWPZWIZ-IDTAVKCVSA-N | CASNo_Ref = {{cascite|correct|??}} | CASNo = 37739-05-2 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 284969 | EINECS = | PubChem = 123807 | IUPHAR_ligand = 374 | SMILES = Clc1nc(c2ncn(c2n1)[C@@H]3O[C@@H]([C@@H](O)[C@H]3O)CO)NC4CCCC4 | InChI = 1/C15H20ClN5O4/c16-15-19-12(18-7-3-1-2-4-7)9-13(20-15)21(6-17-9)14-11(24)10(23)8(5-22)25-14/h6-8,10-11,14,22-24H,1-5H2,(H,18,19,20)/t8-,10-,11-,14-/m1/s1 | RTECS = | MeSHName = 2-chloro-N(6)cyclopentyladenosine | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = }} |Section2={{Chembox Properties | Formula = C15H20ClN5O4 | MolarMass = 369.80 g/mol | Appearance = | Density = | MeltingPt = | MeltingPt_notes = | BoilingPt = | BoilingPt_notes = | Solubility = | SolubleOther = | Solvent = | LogP = | VaporPressure = | HenryConstant = | AtmosphericOHRateConstant = | pKa = | pKb = |Section3={{Chembox Structure | CrystalStruct = | Coordination = | MolShape = |Section4={{Chembox Thermochemistry | DeltaHf = | DeltaHc = | Entropy = | HeatCapacity = |Section5={{Chembox Pharmacology | AdminRoutes = | Bioavail = | Metabolism = | HalfLife = | ProteinBound = | Excretion = | Legal_status = | Legal_US = | Legal_UK = | Legal_AU = | Legal_CA = | Pregnancy_category = | Pregnancy_AU = | Pregnancy_US = |Section6={{Chembox Explosive | ShockSens = | FrictionSens = | DetonationV = | REFactor = |Section7={{Chembox Hazards | EUClass = | MainHazards = | NFPA-H = | NFPA-F = | NFPA-R = | NFPA-S = | RPhrases = | SPhrases = | RSPhrases = | FlashPt = | AutoignitionPt = | ExploLimits = | LD50 = | PEL = |Section8={{Chembox Related | OtherAnions = | OtherCations = | OtherFunction = | OtherFunction_label = | OtherCompounds = }} 2-Chloro-N6-cyclopentyladenosine (CCPA) is a specific receptor agonist for the Adenosine A1 receptor.[1] It is similar to N6-cyclopentyladenosine. References1. ^{{cite journal|author1=Karl-Norbert Klotz|author2=Martin J. Lohse|author3=Ulrich Schwabe|author4=Gloria Cristalli|author5=Sauro Vittori|author6=Mario Grifantini|title= 2-Chloro-N6-[3H]cyclopentyladenosine ([3HCCPA) — a high affinity agonist radioligand for A1 adenosine receptors|journal= Naunyn-Schmiedeberg's Archives of Pharmacology |volume = 340 |year = 1989 |pages = 679–683 |doi = 10.1007/BF00717744 |url = http://www.springerlink.com/content/u723813375h7u5m3/}} {{Adenosinergics}}{{nervous-system-drug-stub}} 5 : Nucleosides|Purines|Organochlorides|Adenosine receptor agonists|Cyclopentanes |
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