| 词条 | Cefminox |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 444377781 | IUPAC_name = (6R,7S)-7-(((((2S)-2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid | image = Cefminox.svg | width = 280 | tradename = | Drugs.com = {{drugs.com|international|cefminox}} | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = Rx-only | routes_of_administration = IM, IV | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 84305-41-9 | ATC_prefix = J01 | ATC_suffix = DC12 | ATC_supplemental = | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1276342 | PubChem = 71141 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | UNII_Ref = {{fdacite|correct|FDA}} | UNII = PW08Y13465 | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D07642 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 64286 | smiles = O=C2N1/C(=C(\\CS[C@@H]1[C@]2(OC)NC(=O)CSC[C@H](C(=O)O)N)CSc3nnnn3C)C(=O)O | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C16H21N7O7S3/c1-22-15(19-20-21-22)33-4-7-3-32-14-16(30-2,13(29)23(14)10(7)12(27)28)18-9(24)6-31-5-8(17)11(25)26/h8,14H,3-6,17H2,1-2H3,(H,18,24)(H,25,26)(H,27,28)/t8-,14-,16+/m1/s1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = JSDXOWVAHXDYCU-VXSYNFHWSA-N | chemical_formula = | C=16 | H=21 | N=7 | O=7 | S=3 | molecular_weight = 519.57 g/mol }}Cefminox (INN) is a second-generation cephalosporin antibiotic.[1][2] SpectrumCefminox is a broad-spectrum, bactericidal cephalosporin antibiotic. It is especially effective against Gram-negative and anaerobic bacteria. The following represents MIC data for a few medically significant microorganisms.
References1. ^{{Cite journal | doi = 10.1007/s150100070027 | last1 = Torres | first1 = A. J. | last2 = Valladares | first2 = L. D. | last3 = Jover | first3 = J. M. | last4 = Sánchez-Pernaute | first4 = A. | last5 = Frías | first5 = J. | last6 = Carcas | first6 = A. J. | last7 = Coronel | first7 = P. | last8 = Ródenas | first8 = E. | last9 = Pérez-Balcabao | first9 = I. | last10 = Fernández-Roblas | first10 = R. | last11 = Moreno | first11 = M. | last12 = Balibrea | first12 = J. L. | title = Cefminox versus metronidazole plus gentamicin intra-abdominal infections: A prospective randomized controlled clinical trial | journal = Infection | volume = 28 | issue = 5 | pages = 318–322 | year = 2000 | pmid = 11073141}} {{Cell wall disruptive antibiotics}}{{antibiotic-stub}}2. ^Patentdocs: Reaction Medium For Methicillin-Resistant Staphylococcus Aureus (Mrsa) Bacteria 3. ^http://www.toku-e.com/Assets/MIC/Cefminox%20sodium.pdf 2 : Cephalosporin antibiotics|Tetrazoles |
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