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词条 Cefpimizole
释义

  1. References

{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 444707809
| IUPAC_name = 2-[1-([(6R,7R)-2-carboxy-7-([(2R)-2-[(5-carboxy1H-imidazole-4-carbonyl)amino]-2-phenylacetyl]amino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl)pyridin-1-ium-4-yl]ethanesulfonate
| image = Cefpimizole.png
| width = 280
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status = Rx-only
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 84880-03-5
| ATC_prefix = none
| ATC_suffix =
| ATC_supplemental =
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 2103902
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 24S58UHU7N
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D03427
| PubChem = 11765031
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 61863
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C28H26N6O10S2/c35-23(18(16-4-2-1-3-5-16)31-24(36)19-20(27(38)39)30-14-29-19)32-21-25(37)34-22(28(40)41)17(13-45-26(21)34)12-33-9-6-15(7-10-33)8-11-46(42,43)44/h1-7,9-10,14,18,21,26H,8,11-13H2,(H5-,29,30,31,32,35,36,38,39,40,41,42,43,44)/t18-,21-,26-/m1/s1
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = LNZMRLHZGOBKAN-KAWPREARSA-N
| chemical_formula =
| C=28 | H=26 | N=6 | O=10 | S=2
| molecular_weight = 670.67 g/mol
| smiles = C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CC=CC=C3)NC(=O)C4=C(N=CN4)C(=O)O)C(=O)[O-])C[N+]5=CC=C(C=C5)CCS(=O)(=O)O
}}

Cefpimizole (INN) is a third-generation cephalosporin antibiotic.

References

  • {{cite journal |author=Hara K, Shimada J |title=[New antimicrobial agent series XXI: Cefpimizole] |language=Japanese |journal=Jpn J Antibiot |volume=40 |issue=6 |pages=1108–22 |date=June 1987 |pmid=3312705 |doi= |url=}}
{{antibiotic-stub}}{{CephalosporinAntiBiotics}}

4 : Cephalosporin antibiotics|Enantiopure drugs|Imidazoles|Pyridines

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