| 词条 | Central nervous system cyst |
| 释义 |
| name = Central nervous system cyst | synonyms = Brain cyst | image = Arachnoid cyst.png | caption = A CT scan of an arachnoid cyst | pronounce = | field = | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }} A central nervous system cyst is a type of cyst that presents and affects part of the central nervous system (CNS). They are usually benign and filled with either cerebrospinal fluid, blood, or tumor cells. CNS cysts are classified into two categories: cysts that originate from non-central nervous system tissue, migrate to, and form on a portion of the CNS, and cysts that originate within central nervous system tissue itself. Within these two categories, there are many types of CNS cysts that have been identified from previous studies. [1][2] ClassificationOriginating from non-central nervous system tissueThese classification of cysts are embedded in the endoderm (inner layer) and the ectoderm (outer layer) of the cranial or spinal cord germ layers. They normally take over the neuraxis, the axis of the central nervous system that determines how the nervous system is placed, which allows the cysts to infiltrate the CNS tissues.[3] They are most commonly found in the area near the pineal gland, the chiasmatic cistern, and the cerebellopontine angle space. These common places generally house extensive and continuously growing cysts.[2] Some examples of cysts originating from non-central nervous system tissue include:
Originating from the central nervous system tissueThis category of cysts takes over areas of necrotic tissue in the brain from injuries, diseases, or abnormalities, which occur due to the central nervous system's nonregenerative nature. These cysts can affect all germ layers of the CNS, but are most common in the arachnoid mater, and the ventricular space, which may block CSF pathways. These cysts can be static (stationary) or progressive. Some examples of cysts originating from the CNS tissue include:
Signs and symptomsSymptoms are assessed on a case by case basis.[5] Some cysts in the CNS can be asymptomatic (producing or showing no symptoms), depending on their location in the brain or spinal cord. If the cysts develop in critical areas of the central nervous system, they can present one or more of the following symptoms:[6]
In general, symptoms vary depending on the type of cyst and its location within the CNS. CausesMany CNS cysts form in the womb during the first few weeks of development as a result of congenital defects.[7] In adults cysts may also form due to a head injury or trauma, resulting in necrotic tissues (dead tissue), and can sometimes be associated with cancerous tumors or infection in the brain. However, the underlying reasons for cyst formation are still unknown.[7] DiagnosisThe diagnostic process typically begins with a medical history workup followed by a medical examination by a physician. Imaging tests, such as CT scans and MRIs, help provide a clearer picture. The physician typically looks for fluid (or other bodily substance) filled sacs to appear in the scans, as is shown in the CT scan of a colloid cyst. A primary health care provider will refer an individual to a neurologist or neurosurgeon for further examination. Other diagnostic methods include radiological examinations and macroscopic examinations. After a diagnosis has been made, immunohistochemistry may be used to differentiate between epithelial cysts and arachnoid cysts.[2] These examinations are useful to get a general idea of possible treatment options, but can be unsatisfactory to diagnose CNS cysts.[3][5] Professionals still do not fully understand how cysts form; however, analyzing the walls of different cyst types, using electron microscopes and light microscopes, TreatmentTreatment is often largely dependent on the type of cyst. Asymptomatic cysts, termed pseudocyst Permanent drainageA neurosurgeon may open a portion of the body and insert a shunt into cerebral spinal fluid (CSF) filled cysts to allow drainage into CSF pathways. The fluid from the cyst is then drained into the abdomen, the body reabsorbs the fluid (reabsorption of fluid does not cause any harm). This type of surgical treatment is often performed to relieve pressure on the brain from a cyst within the cerebral cortex.[3] FenestrationA neurosurgeon performs a craniotomy as a means of entry to access the cyst. The cyst is then opened to release its contents, which are reabsorbed by the brain. [3] This is commonly used with inflammatory cysts located in the ventricles, and can result in increased ventricular fluid flow within the brain. Endoscopic cyst fenestrationA neurosurgeon performs a same day surgery to insert an endoscope, which drains the cyst internally.[3] EpidemiologyCysts derived from CNS tissues are very common in America.[2] They are a subtype of cerebrovascular diseases, which are the third leading cause of death in America.[2] Generally, CNS cysts are present in all geographic regions, races, ages, and sexes.[8] However, certain types of CNS cysts are more prevalent in certain types of individuals than others. Some examples of incidence rates in specific types of cysts include:[1]
References1. ^1 {{Cite web|url=http://www.abta.org/secure/resource-one-sheets/cysts.pdf|title=Cysts|last=Schiff|first=David|date=June 2010|website=American Brain Tumor Association|archive-url=|archive-date=|dead-url=|access-date= 3 March 2017}} 2. ^1 2 3 4 5 {{Cite journal|last=Hirano|first=Asao|last2=Hirano|first2=Michio|date=2004-03-01|title=Benign cysts in the central nervous system: Neuropathological observations of the cyst walls|journal=Neuropathology|language=en|volume=24|issue=1|pages=1–7|doi=10.1111/j.1440-1789.2003.00526.x|issn=1440-1789}} 3. ^1 2 3 4 5 {{Cite news|url=http://weillcornellbrainandspine.org/condition/arachnoid-cysts-intracranial-cysts/surgery-arachnoid-cyst|title=Surgery for an Arachnoid Cyst|last=Greenfield|first=Jerry|date=January 2015|work=Surgery for an Arachnoid cysts|access-date=2017-03-11|archive-url=|archive-date=|dead-url=}} 4. ^{{Cite journal|last=Chen|first=Yong|last2=Fang|first2=Hong-Juan|last3=Li|first3=Zhi-Feng|last4=Yu|first4=Sheng-Yuan|last5=Li|first5=Chu-Zhong|last6=Wu|first6=Zhe-Bao|last7=Zhang|first7=Ya-Zhuo|date=2016-08-01|title=Treatment of Middle Cranial Fossa Arachnoid Cysts: A Systematic Review and Meta-Analysis|url=http://www.sciencedirect.com/science/article/pii/S1878875016304314|journal=World Neurosurgery|volume=92|pages=480–490.e2|doi=10.1016/j.wneu.2016.06.046}} 5. ^1 2 Sundaram C, Paul T R, Raju B V, Ramakrishna Murthy T, Sinha A K, Prasad V S, Purohit A K. Cysts of the central nervous system : a clinicopathologic study of 145 cases. Neurol India [serial online] 2001 [cited 2017 Apr 11];49:237. Available from: http://www.neurologyindia.com/text.asp?2001/49/3/237/1247 6. ^1 2 {{Cite web|url=https://www.saintlukeshealthsystem.org/health-library/brain-cyst|title=Brain Cyst|last=|first=|date=June 2015|website=www.saintlukeshealthsystem.org|archive-url=|archive-date=|dead-url=|access-date=2017-03-26}} 7. ^1 2 3 {{Cite web|url=http://www.cancer.ca/en/cancer-information/cancer-type/brain-spinal/brain-and-spinal-tumours/brain-and-spinal-cord-cysts/?region=on|title=Brain and spinal cord cysts - Canadian Cancer Society|website=www.cancer.ca|language=en|access-date=2017-04-11}} 8. ^{{Cite news|url=https://rarediseases.org/rare-diseases/arachnoid-cysts/|title=Arachnoid Cysts - NORD (National Organization for Rare Disorders)|work=NORD (National Organization for Rare Disorders)|access-date=2017-04-27|language=en-US}} External links{{Medical resources| DiseasesDB = | ICD10 = {{ICD10|G|93|0|g|90}}, {{ICD10|Q|04|6|q|00}} | ICD9 = {{ICD9|348.0}}, {{ICD9|742.4}} | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = D020863 }}{{CNS diseases of the nervous system}}{{Congenital malformations and deformations of nervous system}} 1 : Congenital disorders of nervous system |
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