| 词条 | Cephaeline |
| 释义 |
| verifiedrevid = 708897244 | ImageFile = Cephaeline.svg | IUPACName = (1R)-1-[[(2S,3R,11bS)-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl]methyl]-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol | OtherNames = Cepheline; Desmethylemetine; Dihydropsychotrine |Section1={{Chembox Identifiers | CASNo = 483-17-0 | CASNo_Ref = {{cascite|correct|CAS}} | ChEMBL = 255708 | ChEMBL_Ref = {{ebicite|correct|EBI}} | PubChem = 442195 | UNII = QA971541A1 | UNII_Ref = {{fdacite|correct|FDA}} | ChemSpiderID = 390702 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | SMILES = CC[C@H]1CN2CCc3cc(c(cc3[C@@H]2C[C@@H]1C[C@@H]4c5cc(c(cc5CCN4)O)OC)OC)OC | StdInChI = 1S/C28H38N2O4/c1-5-17-16-30-9-7-19-13-27(33-3)28(34-4)15-22(19)24(30)11-20(17)10-23-21-14-26(32-2)25(31)12-18(21)6-8-29-23/h12-15,17,20,23-24,29,31H,5-11,16H2,1-4H3/t17-,20-,23+,24-/m0/s1 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = DTGZHCFJNDAHEN-OZEXIGSWSA-N | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |Section2={{Chembox Properties | C=28 | H=38 | N=2 | O=4 | Appearance = White silky crystals | Density = | MeltingPt = | BoilingPt = | SolubleOther = Soluble{{vague|date=March 2015}} | Solvent = ethanol |Section3={{Chembox Hazards | MainHazards = Emetic / poisonous | FlashPt = | AutoignitionPt = }} Cephaeline is an alkaloid that is found in Cephaelis ipecacuanha and other plant species including Psychotria acuminata.[1] Cephaeline induces vomiting by stimulating the stomach lining and is found in commercial products such as syrup of ipecac.[2] Chemically, it is closely related to emetine. Poison treatmentCephaeline in the form of syrup of ipecac was once commonly recommended as an emergency treatment for accidental poisoning, but its use has been phased out due to its ineffectiveness.[3] References1. ^{{cite news|url=http://www.accessmylibrary.com/article-1G1-119570434/micropropagaci195179n-de-la-planta.html|title=Micropropagacion de la planta medicinal psychotria acuminata|author1=Lara, Alfonso |author2=Valverde, Roberto |author3=Gomez, Luis |author4=Hidalgo, Nancy | date=July 1, 2003 |work=Agronomía Costarricense| accessdate=26 December 2009}} 2. ^{{cite news|url=http://www.accessmylibrary.com/article-1G1-72449957/pharma-japan-approval-4.html|title=Pharma Japan: Approval of 4 drugs including Seroquel recommended: CPAC panel.|date=November 14, 2000 |work=Chemical Business Newsbase |accessdate=26 December 2009}} 3. ^{{cite journal |journal=Pediatrics |volume=112 |issue=5 |date=November 2003 |pages=1182–1185 |title=Policy statement: Poison treatment in the home |url=http://aappolicy.aappublications.org/cgi/content/full/pediatrics;112/5/1182 |doi=10.1542/peds.112.5.1182 |pmid=14595067 |accessdate=31 December 2009 |archive-url=https://web.archive.org/web/20100706045044/http://aappolicy.aappublications.org/cgi/content/full/pediatrics%3B112/5/1182# |archive-date=2010-07-06 |dead-url=yes |df= }} 7 : Alkaloids|Phenols|Phenol ethers|Tetrahydroisoquinolines|Pyridoisoquinolines|Emetics|Drugs with no legal status |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。