| 释义 |
- Function
- Interactions
- References
- External links
- Further reading
{{Infobox_gene}}Charged multivesicular body protein 1a is a protein that in humans is encoded by the CHMP1A gene.[1][2][3] Function This gene encodes a member of the CHMP/Chmp family of proteins which are involved in multivesicular body sorting of proteins to the interiors of lysosomes. The initial prediction of the protein sequence encoded by this gene suggested that the encoded protein was a metallopeptidase. The nomenclature has been updated recently to reflect the correct biological function of this encoded protein.[3] Interactions CHMP1A has been shown to interact with VPS4A.[1] References 1. ^1 {{cite journal | vauthors = Howard TL, Stauffer DR, Degnin CR, Hollenberg SM | title = CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins | journal = Journal of Cell Science | volume = 114 | issue = Pt 13 | pages = 2395–404 | date = Jul 2001 | pmid = 11559748 | pmc = | doi = }}
2. ^{{cite journal | vauthors = Stauffer DR, Howard TL, Nyun T, Hollenberg SM | title = CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression | journal = Journal of Cell Science | volume = 114 | issue = Pt 13 | pages = 2383–93 | date = Jul 2001 | pmid = 11559747 | pmc = | doi = }}
3. ^1 {{cite web | title = Entrez Gene: PCOLN3 procollagen (type III) N-endopeptidase| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5119| accessdate = }}
External links- {{UCSC gene info|CHMP1A}}
Further reading {{refbegin | 2}}- {{cite journal | vauthors = Nomura N, Nagase T, Miyajima N, Sazuka T, Tanaka A, Sato S, Seki N, Kawarabayasi Y, Ishikawa K, Tabata S | title = Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1 | journal = DNA Research | volume = 1 | issue = 5 | pages = 223–9 | year = 1995 | pmid = 7584044 | doi = 10.1093/dnares/1.5.223 }}
- {{cite journal | vauthors = Scott IC, Halila R, Jenkins JM, Mehan S, Apostolou S, Winqvist R, Callen DF, Prockop DJ, Peltonen L, Kadler KE | title = Molecular cloning, expression and chromosomal localization of a human gene encoding a 33 kDa putative metallopeptidase (PRSM1) | journal = Gene | volume = 174 | issue = 1 | pages = 135–43 | date = Sep 1996 | pmid = 8863740 | doi = 10.1016/0378-1119(96)00510-0 }}
- {{cite journal | vauthors = Yoshida H, Haze K, Yanagi H, Yura T, Mori K | title = Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors | journal = The Journal of Biological Chemistry | volume = 273 | issue = 50 | pages = 33741–9 | date = Dec 1998 | pmid = 9837962 | doi = 10.1074/jbc.273.50.33741 }}
- {{cite journal | vauthors = Tong WY, Nagano-Fujii M, Hidajat R, Deng L, Takigawa Y, Hotta H | title = Physical interaction between hepatitis C virus NS4B protein and CREB-RP/ATF6beta | journal = Biochemical and Biophysical Research Communications | volume = 299 | issue = 3 | pages = 366–72 | date = Dec 2002 | pmid = 12445808 | doi = 10.1016/S0006-291X(02)02638-4 }}
- {{cite journal | vauthors = Strack B, Calistri A, Craig S, Popova E, Göttlinger HG | title = AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding | journal = Cell | volume = 114 | issue = 6 | pages = 689–99 | date = Sep 2003 | pmid = 14505569 | doi = 10.1016/S0092-8674(03)00653-6 }}
- {{cite journal | vauthors = von Schwedler UK, Stuchell M, Müller B, Ward DM, Chung HY, Morita E, Wang HE, Davis T, He GP, Cimbora DM, Scott A, Kräusslich HG, Kaplan J, Morham SG, Sundquist WI | title = The protein network of HIV budding | journal = Cell | volume = 114 | issue = 6 | pages = 701–13 | date = Sep 2003 | pmid = 14505570 | doi = 10.1016/S0092-8674(03)00714-1 }}
- {{cite journal | vauthors = Martin-Serrano J, Yarovoy A, Perez-Caballero D, Bieniasz PD, Yaravoy A | title = Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 21 | pages = 12414–9 | date = Oct 2003 | pmid = 14519844 | pmc = 218772 | doi = 10.1073/pnas.2133846100 }}
- {{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Molecular Systems Biology | volume = 3 | issue = 1 | pages = 89 | year = 2007 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }}
- {{cite journal | vauthors = Row PE, Liu H, Hayes S, Welchman R, Charalabous P, Hofmann K, Clague MJ, Sanderson CM, Urbé S | title = The MIT domain of UBPY constitutes a CHMP binding and endosomal localization signal required for efficient epidermal growth factor receptor degradation | journal = The Journal of Biological Chemistry | volume = 282 | issue = 42 | pages = 30929–37 | date = Oct 2007 | pmid = 17711858 | doi = 10.1074/jbc.M704009200 }}
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