“Chondro-4-sulfatase”的意思、由来-开放百科全书

词条

Chondro-4-sulfatase

释义

References

{{enzyme
| Name = Chondro-4-sulfatase
| EC_number = 3.1.6.9
| CAS_number = 9045-75-4
| IUBMB_EC_number = 3/1/6/9
| GO_code =
| image =
| width =
| caption =
}}

In enzymology, a chondro-4-sulfatase ({{EC number|3.1.6.9}}) is an enzyme that catalyzes the chemical reaction

4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate + H₂O 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine + sulfate

The 3 substrates of this enzyme are 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine, 4-sulfate, and H₂O, whereas its two products are 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine and sulfate.

This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name of this enzyme class is 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine-4-su lfate 4-sulfohydrolase. This enzyme is also called chondroitin-4-sulfatase.

References

{{cite journal | vauthors = Held E, Buddecke E | date = 1967 | title = [Studies on the chemistry of the arterial wall, XI. Demonstration, purification and properties of a chondroitin-4-sulfatase from bovine aorta] | journal = Hoppe-Seyler's Z. Physiol. Chem. | volume = 348 | pages = 1047–60 | pmid = 5595107 | issue = 8 }}
{{cite journal | author = Roy AB | date = 1976 | title = Sulphatases, lysosomes and disease | journal = Aust. J. Exp. Biol. Med. Sci. | volume = 54 | pages = 111–35 | pmid = 13772 | doi = 10.1038/icb.1976.13 | issue = 2 }}
{{cite journal | vauthors = Yamagata T, Saito H, Habuchi O, Suzuki S | date = 1968 | title = Purification and properties of bacterial chondroitinases and chondrosulfatases | journal = J. Biol. Chem. | volume = 243 | pages = 1523–35 | pmid = 5647268 | issue = 7 }}

2 : EC 3.1.6|Enzymes of unknown structure

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