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词条 CHSY1
释义

  1. References

  2. External links

  3. Further reading

{{Infobox_gene}}Chondroitin sulfate synthase 1 is an enzyme that in humans is encoded by the CHSY1 gene.[1][2]

CHSY1 synthesizes chondroitin sulfate, a glycosaminoglycan expressed on the surface of most cells and in extracellular matrices. Glycosaminoglycan chains are covalently linked to a wide range of core protein families and regulate many biologic processes, including cell proliferation and recognition, extracellular matrix deposition, and morphogenesis.[3][4]

References

1. ^{{cite journal | vauthors = Kitagawa H, Uyama T, Sugahara K | title = Molecular cloning and expression of a human chondroitin synthase | journal = J Biol Chem | volume = 276 | issue = 42 | pages = 38721–6 |date=Oct 2001 | pmid = 11514575 | pmc = | doi = 10.1074/jbc.M106871200 }}
2. ^{{cite web|title=Entrez Gene: CHSY1 carbohydrate (chondroitin) synthase 1|url=https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22856}}
3. ^supplied by OMIM
4. ^{{cite web|title=Entrez Gene: CHSY1 carbohydrate (chondroitin) synthase 1|url=https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22856}}

External links

  • {{UCSC gene info|CHSY1}}

Further reading

{{refbegin|2}}
  • {{cite journal | vauthors=Otsuki T, Ota T, Nishikawa T |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117|display-authors=etal}}
  • {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928|display-authors=etal}}
  • {{cite journal | vauthors=Clark HF, Gurney AL, Abaya E |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003 | pmc=403697|display-authors=etal}}
  • {{cite journal | vauthors=Yada T, Sato T, Kaseyama H |title=Chondroitin sulfate synthase-3. Molecular cloning and characterization. |journal=J. Biol. Chem. |volume=278 |issue= 41 |pages= 39711–25 |year= 2003 |pmid= 12907687 |doi= 10.1074/jbc.M304421200|display-authors=etal}}
  • {{cite journal | vauthors=Kitagawa H, Izumikawa T, Uyama T, Sugahara K |title=Molecular cloning of a chondroitin polymerizing factor that cooperates with chondroitin synthase for chondroitin polymerization. |journal=J. Biol. Chem. |volume=278 |issue= 26 |pages= 23666–71 |year= 2003 |pmid= 12716890 |doi= 10.1074/jbc.M302493200}}
  • {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241|display-authors=etal}}
  • {{cite journal | vauthors=Nagase T, Ishikawa K, Suyama M |title=Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 1 |pages= 63–70 |year= 1999 |pmid= 10231032 | doi=10.1093/dnares/6.1.63|display-authors=etal}}
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