| 释义 |
- References
- External links
- Further reading
{{for|the aerodrome using the TC LID, CKS2|Kennisis Lake Water Aerodrome}}{{Infobox_gene}}Cyclin-dependent kinases regulatory subunit 2 is a protein that in humans is encoded by the CKS2 gene.[1][2][3]CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein.[3] References1. ^{{cite journal | vauthors = Richardson HE, Stueland CS, Thomas J, Russell P, Reed SI | title = Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe | journal = Genes Dev | volume = 4 | issue = 8 | pages = 1332–44 |date=Dec 1990 | pmid = 2227411 | pmc = | doi =10.1101/gad.4.8.1332 }}
2. ^{{cite journal | vauthors = Demetrick DJ, Zhang H, Beach DH | title = Chromosomal mapping of the human genes CKS1 to 8q21 and CKS2 to 9q22 | journal = Cytogenet Cell Genet | volume = 73 | issue = 3 | pages = 250–4 |date=Sep 1996 | pmid = 8697818 | pmc = | doi =10.1159/000134349 }}
3. ^1 {{cite web | title = Entrez Gene: CKS2 CDC28 protein kinase regulatory subunit 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1164| accessdate = }}
External linksFurther reading{{refbegin | 2}}- {{cite journal | vauthors=Parge HE, Arvai AS, Murtari DJ |title=Human CksHs2 atomic structure: a role for its hexameric assembly in cell cycle control. |journal=Science |volume=262 |issue= 5132 |pages= 387–95 |year= 1993 |pmid= 8211159 |doi=10.1126/science.8211159 |display-authors=etal}}
- {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
- {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
- {{cite journal | vauthors=Le XF, Lammayot A, Gold D |title=Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling. |journal=J. Biol. Chem. |volume=280 |issue= 3 |pages= 2092–104 |year= 2005 |pmid= 15504738 |doi= 10.1074/jbc.M403080200 |display-authors=etal}}
- {{cite journal | vauthors=Gorr IH, Boos D, Stemmann O |title=Mutual inhibition of separase and Cdk1 by two-step complex formation. |journal=Mol. Cell |volume=19 |issue= 1 |pages= 135–41 |year= 2005 |pmid= 15989971 |doi= 10.1016/j.molcel.2005.05.022 }}
- {{cite journal | vauthors=Stelzl U, Worm U, Lalowski M |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029 |display-authors=etal}}
- {{cite journal | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal}}
- {{cite journal | vauthors=Rother K, Dengl M, Lorenz J |title=Gene expression of cyclin-dependent kinase subunit Cks2 is repressed by the tumor suppressor p53 but not by the related proteins p63 or p73. |journal=FEBS Lett. |volume=581 |issue= 6 |pages= 1166–72 |year= 2007 |pmid= 17336302 |doi= 10.1016/j.febslet.2007.02.028 |display-authors=etal}}
- {{cite journal | vauthors=Bertheau P, Turpin E, Rickman DS |title=Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen. |journal=PLoS Med. |volume=4 |issue= 3 |pages= e90 |year= 2007 |pmid= 17388661 |doi= 10.1371/journal.pmed.0040090 | pmc=1831731 |display-authors=etal}}
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