| 释义 |
- External links
- References
This page provides supplementary chemical data on Cocaine. == Material Safety Data Sheet == The handling of this chemical may incur notable safety precautions. It is highly recommend that you seek the Material Safety Datasheet (MSDS) for this chemical from a reliable source such as [https://web.archive.org/web/20070630043133/http://siri.org/msds/index.php SIRI], and follow its directions. == Structure and properties == | Structure and properties | | Index of refraction, nD | 1.5022 [1] | | Abbe number | ? | | Dielectric constant, εr | ? ε0 at ? °C | | Bond strength | ? | | Bond length | ? | | Bond angle | ? | | Magnetic susceptibility | ? | | Melting Point | 98 °C [1] | | Boiling Point | 187 °C [1] | | Solubility | 1.7 g/L at 25 °C [1] |
== Thermodynamic properties == | Phase behavior | | Triple point | ? K (? °C), ? Pa | | Critical point | ? K (? °C), ? Pa | Std enthalpy change
of fusion, ΔfusHo | ? kJ/mol | Std entropy change
of fusion, ΔfusSo | ? J/(mol·K) | Std enthalpy change
of vaporization, ΔvapHo | ? kJ/mol | Std entropy change
of vaporization, ΔvapSo | ? J/(mol·K) | | Solid properties |
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Std enthalpy change
of formation, ΔfHosolid | ? kJ/mol | Standard molar entropy,
Sosolid | ? J/(mol K) | | Specific heat capacity, cp | ? J/(mol K) | | Liquid properties |
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Std enthalpy change
of formation, ΔfHoliquid | ? kJ/mol | Standard molar entropy,
Soliquid | ? J/(mol K) | | Specific heat capacity, cp | ? J/(mol K) | | Gas properties |
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Std enthalpy change
of formation, ΔfHogas | ? kJ/mol | Standard molar entropy,
Sogas | ? J/(mol K) | | Specific heat capacity, cp | ? J/(mol K) |
== Spectral data == | UV-Vis | | λmax | ? nm | | Extinction coefficient, ε | ? | | IR |
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| Major absorption bands | ? cm−1 | | NMR |
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| Proton NMR | | | Carbon-13 NMR | | | Other NMR data | | | MS |
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Masses of
main fragments | |
External links- [https://www.erowid.org/archive/rhodium/pdf/forensic/1992-2001/cocaine.analogs.nmr-mo-study.pdf Nuclear magnetic resonance and molecular orbital study of some cocaine analogues], includes superposition and overlay of cocaine, cocaine derivatives, and their minimum energy values.
- [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058377/ Conformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocation], thorough-going elucidation of exact mechanism and mode of action specific to cocaine at the dopamine transporter.
- [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779727/ Genome Wide Analysis of Chromatin Regulation by Cocaine Reveals a Novel Role for Sirtuins]
References 1. ^1 2 3 {{cite book|author=D. R. Lide|title=CRC Handbook of Chemistry and Physics 89th edition|publisher=CRC press|year=2009}}
Except where noted otherwise, data relate to standard ambient temperature and pressure. Disclaimer applies. 1 : Chemical data pages |