| 词条 | Collecting duct carcinoma |
| 释义 |
| name = Collecting duct carcinoma | synonyms = | image = Collecting duct carcinoma - 2 WBAL.tif | caption = Collecting duct carcinoma. H&E stain. | pronounce = | field = oncology/nephrology | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }} Collecting duct carcinoma (CDC) (also known as Bellini duct carcinoma[1]), is a type of kidney cancer that originates in the papillary duct of the kidney. It is rare, accounting for 1-3% of all kidney cancers.[2] It is also recently described; a 2002 review found just 40 case reports worldwide.[3] Previously, due to its location, CDC was commonly diagnosed as renal cell carcinoma or a subtype of renal cell carcinoma.[4] However, CDC does not respond well to chemotherapy drugs used for renal cell carcinoma, and progresses and spreads more quickly. Signs and symptomsSigns and symptoms are as for kidney cancer. HistologyHistologic examination of collecting duct carcinoma demonstrates an infiltrative lesion with tubulopapillary, irregular channels lined by high grade hobnail cells with marked desmoplastic response and brisk neutrophilic infiltrate. Treatment{{Empty section|date=February 2018}}HistoryCDC was thought to be renal cell carcinoma, until "recently developed techniques of lectin histochemistry" helped forward knowledge of kidney duct cancers.[5] References1. ^{{cite journal| vauthors = Amin MB, MacLennan GT, Gupta R, Grignon D, Paraf F, Vieillefond A, Paner GP, Stovsky M, Young AN, Srigley JR, Cheville JC| title = Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma| journal = Am. J. Surg. Pathol.| volume = 33| issue = 3| pages = 384–92| date = March 2009| pmid = 19011562| doi = 10.1097/PAS.0b013e3181872d3f| url =}} 2. ^{{cite journal| vauthors = Fakhrai N, Haitel A, Balassy C, Zielinski CC, Schmidinger M| title = Major response and clinical benefit following third-line treatment for Bellini duct carcinoma| journal = Wien. Klin. Wochenschr.| volume = 117| issue = 1–2| pages = 63–5| date = January 2005| pmid = 15986594| doi = 10.1007/s00508-004-0289-4| url =}} 3. ^{{cite journal| vauthors = Singh I, Nabi G| title = Bellini duct carcinoma: review of diagnosis and management| journal = Int Urol Nephrol| volume = 34| issue = 1| pages = 91–5| year = 2002| pmid = 12549647| doi = 10.1023/A:1021315130481| url = http://www.kluweronline.com/art.pdf?issn=0301-1623&volume=34&page=91}} 4. ^{{cite journal| vauthors = Méjean A, Rouprêt M, Larousserie F, Hopirtean V, Thiounn N, Dufour B| title = Is there a place for radical nephrectomy in the presence of metastatic collecting duct (Bellini) carcinoma?| journal = J. Urol.| volume = 169| issue = 4| pages = 1287–90| date = April 2003| pmid = 12629344| doi = 10.1097/01.ju.0000050221.51509.f5| url = http://linkinghub.elsevier.com/retrieve/pii/S0022-5347(05)63742-1}} 5. ^{{cite journal |author=O Natsume |author2=S Ozono |author3=T Futami |author4=M Ohta |last-author-amp=yes |year=1997 |title=Bellini duct carcinoma: a case report |journal=Japanese Journal of Clinical Oncology |volume=27 |issue=2 |pages=107–110 |publisher= |location= |doi=10.1093/jjco/27.2.107 |url=http://jjco.oxfordjournals.org/cgi/content/full/27/2/107 |accessdate=2008-06-03 |pmid=9152800}} External links{{Medical resources| DiseasesDB = | ICD10 = C64 | ICD9 = | ICDO = | OMIM = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeshID = D002292 | Orphanet = 247203 }} 2 : Rare cancers|Kidney cancer |
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