词条 | Homoserine |
释义 |
| Verifiedimages = changed | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 461770636 | Name = L-Homoserine | ImageFile_Ref = {{chemboximage|correct|??}} | ImageFile = L-Homoserin.svg | ImageSize = 180px | ImageName = Skeletal formula | ImageFile1 = L-Homoserine-zwitterion-3D-balls.png | ImageSize1 = 120px | ImageName1 = Ball-and-stick model of the zwitterion | IUPACName = (S)-2-Amino-4-hydroxybutanoic acid |Section1={{Chembox Identifiers | InChI = 1/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8) | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = 30653 | SMILES = O=C(O)C(N)CCO | InChIKey = UKAUYVFTDYCKQA-UHFFFAOYAZ | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C4H9NO3/c5-3(1-2-6)4(7)8/h3,6H,1-2,5H2,(H,7,8) | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = UKAUYVFTDYCKQA-UHFFFAOYSA-N | CASNo = 672-15-1 | CASNo_Ref = {{cascite|correct|CAS}} | EC_number = 211-590-6 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 758 | PubChem = 779 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 11722 }} |Section2={{Chembox Properties | Formula = C4H9NO3 | MolarMass = 119.12 g/mol | MeltingPt = 203 °C (decomposes) }} Homoserine (also called isothreonine) is an α-amino acid with the chemical formula HO2CCH(NH2)CH2CH2OH. L-Homoserine is not one of the common amino acids encoded by DNA. It differs from the proteinogenic amino acid serine by insertion of an additional -CH2- unit into the backbone. Homoserine, or its lactone form, is the product of a cyanogen bromide cleavage of a peptide by degradation of methionine. Homoserine is an intermediate in the biosynthesis of three essential amino acids: methionine, threonine (an isomer of homoserine), and isoleucine. It forms by two reductions of aspartic acid via the intermediacy of aspartate semialdehyde.[1] References1. ^Berg, J. M.; Stryer, L. et al. (2002), Biochemistry. W.H. Freeman. {{ISBN|0-7167-4684-0}} {{biochem-stub}} 2 : Amino acids|Non-proteinogenic amino acids |
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