| 词条 | Coumermycin A1 |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 387419821 | IUPAC_name = 3-methyl-1H-pyrrole-2,4-diyl)bis[carbonylimino(4-hydroxy-8-methyl-2-oxo-2H-chromene-3,7-diyl)oxy(2R,3R,4S,5R)-3-hydroxy-5-methoxy-6,6-dimethyltetrahydro-2H-pyran-2,4-diyl] bis(5-methyl-1H-pyrrole-2-carboxylate | image = Coumermycin-A1-2.png | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 4434-05-3 | UNII_Ref = {{fdacite|changed|FDA}} | UNII = PCH9QZ1IIH | ATC_prefix = none | ATC_suffix = | PubChem = 54675768 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 389471 | ChEBI_Ref = {{ebicite|changed|EBI}} | ChEBI = 3907 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 16736904 | C=55 | H=59 | N=5 | O=20 | molecular_weight = 1110.08 g/mol | smiles = CO[C@@H]1[C@H](OC(=O)c2ccc(C)[nH]2)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4c[nH]c(C(=O)Nc5c(=O)oc6c(C)c(ccc6c5O)O[C@@H]5OC(C)(C)[C@H](OC)[C@H](OC(=O)c6ccc(C)[nH]6)[C@H]5O)c4C)c(=O)oc3c2C)OC1(C)C | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C55H59N5O20/c1-21-12-16-29(57-21)48(67)77-42-38(63)52(79-54(6,7)44(42)71-10)73-31-18-14-26-36(61)34(50(69)75-40(26)24(31)4)59-46(65)28-20-56-33(23(28)3)47(66)60-35-37(62)27-15-19-32(25(5)41(27)76-51(35)70)74-53-39(64)43(45(72-11)55(8,9)80-53)78-49(68)30-17-13-22(2)58-30/h12-20,38-39,42-45,52-53,56-58,61-64H,1-11H3,(H,59,65)(H,60,66)/t38-,39-,42+,43+,44-,45-,52-,53-/m1/s1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = WTIJXIZOODAMJT-DHFGXMAYSA-N | synonyms = Coumamycin }}Coumermycin A1 is an aminocoumarin.[1][2] See alsoChemically induced dimerizationReferences1. ^{{Cite journal| first1 = L.| title = Genetic engineering of antibiotic biosynthesis for the generation of new aminocoumarins| journal = Biotechnology Advances| volume = 27| last1 = Heide| issue = 6| pages = 1006–1014| year = 2009| pmid = 19463934| doi = 10.1016/j.biotechadv.2009.05.017}} {{Nucleic acid inhibitors}}{{antibiotic-stub}}2. ^{{Cite journal| pmid = 18473891| year = 2008| last1 = Heide | first1 = L.| last2 = Gust| last3 = Anderle| last4 = Li| title = Combinatorial biosynthesis, metabolic engineering and mutasynthesis for the generation of new aminocoumarin antibiotics| volume = 8| issue = 8| pages = 667–679| journal = Current Topics in Medicinal Chemistry| doi = 10.2174/156802608784221505 | first2 = B. | first3 = C. | first4 = S. M.}} 2 : Antibiotics|Imidazoles |
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