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词条 CRL-40,941
释义

  1. See also

  2. References

{{Multiple issues|{{refimprove|date=April 2014}}{{notability|date=April 2014}}
}}{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 451554065
| IUPAC_name = 2[Bis(4-fluorophenyl)methyl]sulfinylN-hydroxyacetamide
| synonyms = Fluorafinil, Fladrafinil
| image = CRL-40,941.svg
| tradename =
| pregnancy_category =
| legal_US_comment = Not approved
| routes_of_administration = Oral
| bioavailability =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number =90212-80-9
| ATC_prefix = none
| ATC_suffix =
| PubChem = 13316557
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 29785194
| C=15 | H=13 | F=2 | N=1 | O=3 | S=1
| molecular_weight = 325.33 g/mol
| smiles = C1=CC(=CC=C1C(C2=CC=C(C=C2)F)S(=O)CC(=O)NO)F
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C15H13F2NO3S/c16-12-5-1-10(2-6-12)15(22(21)9-14(19)18-20)11-3-7-13(17)8-4-11/h1-8,15,20H,9H2,(H,18,19)
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = VKGUUSVYPXTWMA-UHFFFAOYSA-N
}}CRL-40,941 (also known as fladrafinil and fluorafinil) is a eugeroic closely related to adrafinil and modafinil. It is the bis(p-fluoro) ring-substituted derivative of adrafinil. CRL-40,941 was found to produce antiaggressive effects in animals, which adrafinil does not produce.[1]

See also

  • Adrafinil
  • Armodafinil
  • CRL-40,940
  • Fluorenol
  • Modafinil
  • JJC8-016 is brand new (2017).

References

1. ^{{ cite patent | country = US | status = patent | number = 4489095 | inventor = Lafon, L. | title = Halogenobenzhydrylsulfinylacetohydroxamic Acids | gdate = 1984-12-18 | assign1 = Laboratoire L. Lafon }}
{{Stimulants}}{{nervous-system-drug-stub}}

9 : Abandoned drugs|Benzene derivatives|Designer drugs|Drugs with unknown mechanisms of action|Fluoroarenes|Hydroxamic acids|Prodrugs|Stimulants|Sulfoxides

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