词条 | CRL-40,941 |
释义 |
}}{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 451554065 | IUPAC_name = 2[Bis(4-fluorophenyl)methyl]sulfinylN-hydroxyacetamide | synonyms = Fluorafinil, Fladrafinil | image = CRL-40,941.svg | tradename = | pregnancy_category = | legal_US_comment = Not approved | routes_of_administration = Oral | bioavailability = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number =90212-80-9 | ATC_prefix = none | ATC_suffix = | PubChem = 13316557 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 29785194 | C=15 | H=13 | F=2 | N=1 | O=3 | S=1 | molecular_weight = 325.33 g/mol | smiles = C1=CC(=CC=C1C(C2=CC=C(C=C2)F)S(=O)CC(=O)NO)F | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C15H13F2NO3S/c16-12-5-1-10(2-6-12)15(22(21)9-14(19)18-20)11-3-7-13(17)8-4-11/h1-8,15,20H,9H2,(H,18,19) | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = VKGUUSVYPXTWMA-UHFFFAOYSA-N }}CRL-40,941 (also known as fladrafinil and fluorafinil) is a eugeroic closely related to adrafinil and modafinil. It is the bis(p-fluoro) ring-substituted derivative of adrafinil. CRL-40,941 was found to produce antiaggressive effects in animals, which adrafinil does not produce.[1] See also
References1. ^{{ cite patent | country = US | status = patent | number = 4489095 | inventor = Lafon, L. | title = Halogenobenzhydrylsulfinylacetohydroxamic Acids | gdate = 1984-12-18 | assign1 = Laboratoire L. Lafon }} {{Stimulants}}{{nervous-system-drug-stub}} 9 : Abandoned drugs|Benzene derivatives|Designer drugs|Drugs with unknown mechanisms of action|Fluoroarenes|Hydroxamic acids|Prodrugs|Stimulants|Sulfoxides |
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