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词条 Cyfluthrin
释义

  1. Safety

  2. Commercial use

  3. See also

  4. References

{{chembox
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| Watchedfields = changed
| verifiedrevid = 449713431
| ImageFile1 = Cyfluthrin Marco 201809017.svg
| ImageFile2 = Cyfluthrin 3D.png
| IUPACName = [(R)-cyano-[4-fluoro-3-(phenoxy)phenyl]methyl] (1R,3R)-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate
| OtherNames =
|Section1={{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 45482
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = SCM2QLZ6S0
| InChI = 1/C22H18Cl2FNO3/c1-22(2)15(11-19(23)24)20(22)21(27)29-18(12-26)13-8-9-16(25)17(10-13)28-14-6-4-3-5-7-14/h3-11,15,18,20H,1-2H3/t15-,18-,20-/m0/s1
| InChIKey = QQODLKZGRKWIFG-QSFXBCCZBF
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C22H18Cl2FNO3/c1-22(2)15(11-19(23)24)20(22)21(27)29-18(12-26)13-8-9-16(25)17(10-13)28-14-6-4-3-5-7-14/h3-11,15,18,20H,1-2H3/t15-,18-,20-/m0/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = QQODLKZGRKWIFG-QSFXBCCZSA-N
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo = 68359-37-5
| PubChem = 50153
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 2104608
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = C10982
| SMILES = Cl/C(Cl)=C/[C@H]3[C@@H](C(=O)O[C@@H](C#N)c2ccc(F)c(Oc1ccccc1)c2)C3(C)C
}}
|Section2={{Chembox Properties
| C=22 | H=18 | Cl=2 | F=1 | N=1 | O=3
| Appearance =
| Density =
| MeltingPtC = 60
| BoilingPt =
| Solubility = 2 μg/L}}
|Section6={{Chembox Pharmacology
| ATCCode_prefix = P03
| ATCCode_suffix = BA01
| ATC_Supplemental = {{ATCvet|P53|AC12}}
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|Section7={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt = }}
}}

Cyfluthrin is a pyrethroid insecticide and common household pesticide. It is a complex organic compound and the commercial product is sold as a mixture of isomers. Like most pyrethroids, it is highly toxic to fish and invertebrates, but it is far less toxic to humans.[1] It is generally supplied as a 10–25% liquid concentrate for commercial use and is diluted prior to spraying onto agricultural crops and outbuildings.

Safety

In rats, the {{LD50}}s are 500, 800 (oral), and 600 (skin) mg/kg.[1]

Excessive exposure can cause nausea, headache, muscle weakness, salivation, shortness of breath and seizures. In humans, it is deactivated by enzymatic hydrolysis to several carboxylic acid metabolites, whose urinary excretion half-lives are in a range of 5–7 hours. Worker exposure to the chemical can be monitored by measurement of the urinary metabolites, while severe overdosage may be confirmed by quantification of cyfluthrin in blood or plasma.[2]

Health and safety risks are controlled by right to know laws that exist in most developed countries. Cyfluthrin is regulated in the US by the EPA.[3]

Commercial use

Cyfluthrin is used in insecticidal sprays such as Temprid, an odourless insecticide mix (Bayer) which uses a combination of (beta-) cyfluthrin and imidacloprid, a residual control agent.

See also

  • Cyhalothrin

References

1. ^{{cite book | author = Robert L. Metcalf | chapter = Insect Control | title = Ullmann’s Encyclopedia of Industrial Chemistry | publisher = Wiley-VCH | location = Weinheim | year = 2002 | doi = 10.1002/14356007.a14_263}}
2. ^{{Cite book|author = R. Baselt | title = Disposition of Toxic Drugs and Chemicals in Man | edition = 8th | publisher = Biomedical Publications | location = Foster City, CA | year = 2008 | pages = 388–389}}
3. ^{{cite web|url=http://www.epa.gov/oppsrrd1/reevaluation/pyrethroids-pyrethrins.html|title=Pyrethroids and Pyrethrins|publisher=United States Environmental Protection Agency}}
{{insecticides}}

8 : Fluoroarenes|Pyrethroids|Organochlorides|Nitriles|Phenol ethers|Cyclopropanes|Carboxylate esters|Cyanohydrin esters

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