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词条 Cytidylate kinase
释义

  1. References

  2. Further reading

{{enzyme
| Name = cytidylate kinase
| EC_number = 2.7.4.14
| CAS_number = 37278-21-0
| IUBMB_EC_number = 2/7/4/14
| GO_code = 0004127
| image =
| width =
| caption =
}}

In enzymology, a cytidylate kinase ({{EC number|2.7.4.14}}) is an enzyme that catalyzes the chemical reaction

ATP + (d)CMP ADP + (d)CDP

Thus, the two substrates of this enzyme are ATP and dCMP, whereas its two products are ADP and dCDP.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is ATP:CMP phosphotransferase. Other names in common use include: deoxycytidylate kinase, deoxycytidylate kinase, CMP kinase, CTP:CMP phosphotransferase, dCMP kinase, deoxycytidine monophosphokinase, UMP-CMP kinase, ATP:UMP-CMP phosphotransferase, and pyrimidine nucleoside monophosphate kinase. This enzyme participates in pyrimidine metabolism.

References

Further reading

{{refbegin}}
  • {{cite journal | vauthors = Hurwitz J | date = 1959 | title = The enzymatic incorporation of ribonucleotides into polydeoxynucleotide material | journal = J. Biol. Chem. | volume = 234 | pages = 2351–2358 }}
  • {{cite book | veditors = Boyer PD, Lardy H, Myrback K | title = The Enzymes | edition = 2nd | volume = 6 | publisher = Academic Press | location = New York | year = 1962 | pages = 139–149 }}
  • {{cite journal | vauthors = Ruffner BW, Anderson EP | title = Adenosine triphosphate: uridine monophosphate-cytidine monophosphate phosphotransferase from Tetrahymena pyriformis | journal = The Journal of Biological Chemistry | volume = 244 | issue = 21 | pages = 5994–6002 | date = November 1969 | pmid = 5350952 }}
{{refend}}{{Kinases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{2.7-enzyme-stub}}

2 : EC 2.7.4|Enzymes of known structure

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