| 释义 |
- Interactions
- References
- Further reading
{{Infobox_gene}}Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 is a protein that in humans is encoded by the ASAP1 gene.[1][2]InteractionsDDEF1 has been shown to interact with Src.[3] References1. ^{{cite journal | vauthors = Brown MT, Andrade J, Radhakrishna H, Donaldson JG, Cooper JA, Randazzo PA | title = ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src | journal = Mol Cell Biol | volume = 18 | issue = 12 | pages = 7038–51 |date=Dec 1998 | pmid = 9819391 | pmc = 109286 | doi = }}
2. ^{{cite web | title = Entrez Gene: DDEF1 development and differentiation enhancing factor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=50807| accessdate = }}
3. ^{{cite journal |last=Brown |first=M T |author2=Andrade J |author3=Radhakrishna H |author4=Donaldson J G |author5=Cooper J A |author6=Randazzo P A |date=Dec 1998 |title=ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src |journal=Mol. Cell. Biol. |volume=18 |issue=12 |pages=7038–51 |publisher= |location = UNITED STATES| issn = 0270-7306| pmid = 9819391 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=109286 }}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Nagase T, Ishikawa K, Kikuno R |title=Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 5 |pages= 337–45 |year= 2000 |pmid= 10574462 |doi=10.1093/dnares/6.5.337 |display-authors=etal}}
- {{cite journal | vauthors=Furman C, Short SM, Subramanian RR |title=DEF-1/ASAP1 is a GTPase-activating protein (GAP) for ARF1 that enhances cell motility through a GAP-dependent mechanism. |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 7962–9 |year= 2002 |pmid= 11773070 |doi= 10.1074/jbc.M109149200 |display-authors=etal}}
- {{cite journal | vauthors=Scott MP, Zappacosta F, Kim EY |title=Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1. |journal=J. Biol. Chem. |volume=277 |issue= 31 |pages= 28238–46 |year= 2002 |pmid= 12029088 |doi= 10.1074/jbc.M202783200 |display-authors=etal}}
- {{cite journal | vauthors=Liu Y, Loijens JC, Martin KH |title=The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly. |journal=Mol. Biol. Cell |volume=13 |issue= 6 |pages= 2147–56 |year= 2002 |pmid= 12058076 |doi= 10.1091/mbc.E02-01-0018 | pmc=117631 |display-authors=etal}}
- {{cite journal | vauthors=Oshiro T, Koyama S, Sugiyama S |title=Interaction of POB1, a downstream molecule of small G protein Ral, with PAG2, a paxillin-binding protein, is involved in cell migration. |journal=J. Biol. Chem. |volume=277 |issue= 41 |pages= 38618–26 |year= 2002 |pmid= 12149250 |doi= 10.1074/jbc.M203453200 |display-authors=etal}}
- {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal|bibcode=2002PNAS...9916899M }}
- {{cite journal | vauthors=Oda A, Wada I, Miura K |title=CrkL directs ASAP1 to peripheral focal adhesions. |journal=J. Biol. Chem. |volume=278 |issue= 8 |pages= 6456–60 |year= 2003 |pmid= 12522101 |doi= 10.1074/jbc.M210817200 |display-authors=etal}}
- {{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
- {{cite journal | vauthors=Onodera Y, Hashimoto S, Hashimoto A |title=Expression of AMAP1, an ArfGAP, provides novel targets to inhibit breast cancer invasive activities. |journal=EMBO J. |volume=24 |issue= 5 |pages= 963–73 |year= 2005 |pmid= 15719014 |doi= 10.1038/sj.emboj.7600588 | pmc=554134 |display-authors=etal}}
- {{cite journal | vauthors=Ehlers JP, Worley L, Onken MD, Harbour JW |title=DDEF1 is located in an amplified region of chromosome 8q and is overexpressed in uveal melanoma. |journal=Clin. Cancer Res. |volume=11 |issue= 10 |pages= 3609–13 |year= 2005 |pmid= 15897555 |doi= 10.1158/1078-0432.CCR-04-1941 }}
- {{cite journal | vauthors=Che MM, Boja ES, Yoon HY |title=Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains. |journal=Cell. Signal. |volume=17 |issue= 10 |pages= 1276–88 |year= 2005 |pmid= 16038802 |doi= 10.1016/j.cellsig.2005.01.007 |display-authors=etal}}
- {{cite journal | vauthors=Nusbaum C, Mikkelsen TS, Zody MC |title=DNA sequence and analysis of human chromosome 8. |journal=Nature |volume=439 |issue= 7074 |pages= 331–5 |year= 2006 |pmid= 16421571 |doi= 10.1038/nature04406 |display-authors=etal|bibcode=2006Natur.439..331N }}
- {{cite journal | vauthors=Hashimoto S, Hirose M, Hashimoto A |title=Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 18 |pages= 7036–41 |year= 2006 |pmid= 16636290 |doi= 10.1073/pnas.0509166103 | pmc=1459014 |display-authors=etal|bibcode=2006PNAS..103.7036H }}
{{refend}}{{PDB Gallery|geneid=50807}}{{gene-8-stub}} |