Desbiens may refer to:

• Desbiens, Quebec, a ville in the Canadian province of Quebec
• Guillaume Desbiens, Canadian ice hockey player
• Jean-Paul Desbiens, Quebec writer, journalist, teacher
• Laurent Desbiens, former French cyclist

• Osceola Mills
• Osceola Outlaws
• Osceola station
• Osceola & St Croix Valley Railway
• Osceola Township, Stark County, Illinois
• Osceola, West Virginia
• OSCE Parliamentary Assembly
• OSCE Representative on Freedom of the Media
• Oschatz
• Oschersleben
• Oschersleben (Bode)
• Oschersleben (Bode) (Verwaltungsgemeinschaft)
• Oschersleben (Verwaltungsgemeinschaft)
• Oschiri
• Oschophoria
• Oscilioscope
• Oscilla
• Oscillating
• Oscillating circuit
• Oscillating circuits
• Oscillating differential equation
• Oscillating Path Rolling Ball Clock
• Oscillating reaction
• Oscillating saw
• Oscillating two-stream instability