| 词条 | Diosmetin |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 401008559 | Name = Diosmetin | ImageFile = Diosmetin.svg | ImageSize = 220px | ImageName = Diosmetin structure | ImageFile1 = Diosmetin molecule ball.png | ImageSize1 = 220 | ImageAlt1 = Ball-and-stick model of diosmetin | IUPACName = 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one | OtherNames = Luteolin 4'-methyl ether 3′,5,7-trihydroxy-4′-methoxyflavone |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo= 520-34-3 | UNII_Ref = {{fdacite|changed|FDA}} | UNII = TWZ37241OT | SMILES = COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 4444931 | InChI = 1/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3 | InChIKey = MBNGWHIJMBWFHU-UHFFFAOYAU | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = MBNGWHIJMBWFHU-UHFFFAOYSA-N | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 90568 | ChEBI_Ref = {{ebicite|changed|EBI}} | ChEBI = 4630 | PubChem = 5281612 |Section2={{Chembox Properties | Formula = C16H12O6 | MolarMass = 300.26 g/mol | Density = | MeltingPt = | BoilingPt = }}Diosmetin, also known as 5,7,3'-trihydroxy-4'-methoxyflavone, is an O-methylated flavone, a chemical compound that can be found in the Caucasian vetch.[1] It has been found to act as a weak TrkB receptor agonist.[2] GlycosidesDiosmetin is the diosmin aglycone. See also
References1. ^Diosmetin glycosides from caucasian vetch: Isolation and study of biological activity {{Flavones}}{{Growth factor receptor modulators}}{{Natural-phenol-stub}}O. A. Andreeva, M. N. Ivashev, I. I. Ozimina and G. V. Maslikova, 1994 2. ^{{cite journal | vauthors = Jang SW, Liu X, Yepes M, Shepherd KR, Miller GW, Liu Y, Wilson WD, Xiao G, Blanchi B, Sun YE, Ye K | title = A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 107 | issue = 6 | pages = 2687–92 | year = 2010 | pmid = 20133810 | pmc = 2823863 | doi = 10.1073/pnas.0913572107 | url = http://www.pnas.org/cgi/pmidlookup?view=long&pmid=20133810}} 3 : O-Methylated flavones|Resorcinols|TrkB agonists |
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