Domestic Science Building may refer to:

• Domestic Science Building (Normal, Alabama), listed on the National Register of Historic Places in Madison County, Alabama
• Domestic Science Building (Arkadelphia, Arkansas), NRHP-listed
• Girls' Domestic Science and Arts Building, Russellville, Arkansas, NRHP-listed
• Domestic Science and Manual Training School, St. Petersburg, Florida, NRHP-listed

• 7886 Redman
• 7887 Bratfest
• 788 in poetry
• 788 (number)
• 788th Bombardment Squadron
• 7 8 9
• 78905 Seanokeefe
• 7890 Yasuofukui
• 7891 Fuchie
• 7892 Musamurahigashi
• 78-94 Foregate Street, Chester
• 7894 Rogers
• 7895 Kaseda
• 7896 Svejk
• 7896 Švejk
• 7897 Bohuska
• 7897 Bohuška
• 7898 Ohkuma
• 7899 Joya
• 789 in poetry
• 789 (number)
• 789 series
• 789 (song)
• 7 8 9 (song)
• 789th Aircraft Control and Warning Squadron