请输入您要查询的百科知识：

　

词条 DPP3
释义

  1. References

  2. Further reading

  3. External links

{{Underlinked|date=May 2016}}{{Infobox_gene}}Dipeptidyl-peptidase 3 is an enzyme that in humans is encoded by the DPP3 gene.[1][2]

This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized.[2]

References

1. ^{{cite journal | vauthors = Fukasawa KM, Fukasawa K, Harada M | title = Assignment of the dipeptidyl peptidase III gene (DPP3) to human chromosome 11 band q12→q13.1 by in situ hybridization | journal = Cytogenet Cell Genet | volume = 88 | issue = 1–2 | pages = 99–100 |date=Jun 2000 | pmid = 10773679 | pmc = | doi =10.1159/000015498 }}
2. ^1 {{cite web | title = Entrez Gene: DPP3 dipeptidyl-peptidase 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10072| accessdate = }}

Further reading

{{refbegin | 2}}
  • {{cite journal | vauthors=Kar NC, Pearson CM |title=Dipeptidyl peptidases in human muscle disease |journal=Clin. Chim. Acta |volume=82 |issue= 1–2 |pages= 185–92 |year= 1978 |pmid= 618680 |doi=10.1016/0009-8981(78)90042-6 }}
  • {{cite journal | vauthors=Grdisa M, Vitale L |title=Types and localization of aminopeptidases in different human blood cells |journal=Int. J. Biochem. |volume=23 |issue= 3 |pages= 339–45 |year= 1991 |pmid= 2044841 |doi=10.1016/0020-711X(91)90116-5 }}
  • {{cite journal | vauthors=Swanson AA, Davis RM, Meinhardt NC |title=Proteases in human lenses and their possible significance |journal=Curr. Eye Res. |volume=4 |issue= 1 |pages= 43–8 |year= 1985 |pmid= 2858361 |doi=10.3109/02713688508999965 }}
  • {{cite journal | author=Vanha-Perttula T |title=Dipeptidyl peptidase III and alanyl aminopeptidase in the human seminal plasma: origin and biochemical properties |journal=Clin. Chim. Acta |volume=177 |issue= 2 |pages= 179–95 |year= 1989 |pmid= 2906822 |doi=10.1016/0009-8981(88)90140-4 }}
  • {{cite journal | vauthors=Shimamori Y, Watanabe Y, Fujimoto Y |title=Human placental dipeptidyl aminopeptidase III: hydrolysis of enkephalins and its stimulation by cobaltous ion |journal=Biochem. Med. Metab. Biol. |volume=40 |issue= 3 |pages= 305–10 |year= 1989 |pmid= 3233187 |doi=10.1016/0885-4505(88)90133-8 }}
  • {{cite journal | vauthors=Abramić M, Zubanović M, Vitale L |title=Dipeptidyl peptidase III from human erythrocytes |journal=Biol. Chem. Hoppe-Seyler |volume=369 |issue= 1 |pages= 29–38 |year= 1988 |pmid= 3348886 |doi=10.1515/bchm3.1988.369.1.29 }}
  • {{cite journal | vauthors=Shimamori Y, Watanabe Y, Fujimoto Y |title=Purification and characterization of dipeptidyl aminopeptidase III from human placenta |journal=Chem. Pharm. Bull. |volume=34 |issue= 8 |pages= 3333–40 |year= 1987 |pmid= 3791505 |doi= 10.1248/cpb.34.3333}}
  • {{cite journal | vauthors=Swanson AA, Davis RM, McDonald JK |title=Dipeptidyl peptidase III of human cataractous lenses. Partial purification |journal=Curr. Eye Res. |volume=3 |issue= 2 |pages= 287–91 |year= 1984 |pmid= 6368131 |doi=10.3109/02713688408997211 }}
  • {{cite journal | vauthors=Jones TH, Kapralou A |title=A rapid assay for dipeptidyl aminopeptidase III in human erythrocytes |journal=Anal. Biochem. |volume=119 |issue= 2 |pages= 418–23 |year= 1982 |pmid= 7041700 |doi=10.1016/0003-2697(82)90607-8 }}
  • {{cite journal | vauthors=Vitale L, Zubanović M, Abramić M |title=Properties and distribution of aminopeptidase and dipeptidyl aminopeptidase III of human erythrocytes |journal=Acta Biol. Med. Ger. |volume=40 |issue= 10–11 |pages= 1489–95 |year= 1982 |pmid= 7044004 |doi= }}
  • {{cite journal | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
  • {{cite journal | vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3 |display-authors=etal}}
  • {{cite journal | vauthors=Fukasawa K, Fukasawa KM, Kanai M |title=Dipeptidyl peptidase III is a zinc metallo-exopeptidase. Molecular cloning and expression |journal=Biochem. J. |volume=329 ( Pt 2) |issue= Pt 2|pages= 275–82 |year= 1998 |pmid= 9425109 |doi= | pmc=1219041 |display-authors=etal}}
  • {{cite journal | vauthors=Simaga S, Babić D, Osmak M |title=Dipeptidyl peptidase III in malignant and non-malignant gynaecological tissue |journal=Eur. J. Cancer |volume=34 |issue= 3 |pages= 399–405 |year= 1998 |pmid= 9640230 |doi=10.1016/S0959-8049(97)00401-2 |display-authors=etal}}
  • {{cite journal | vauthors=Akiyama T, Harada S, Kojima F |title=Fluostatins A and B, new inhibitors of dipeptidyl peptidase III, produced by Streptomyces sp. TA-3391. I. Taxonomy of producing strain, production, isolation, physico-chemical properties and biological properties |journal=J. Antibiot. |volume=51 |issue= 6 |pages= 553–9 |year= 1998 |pmid= 9711218 |doi= 10.7164/antibiotics.51.553|display-authors=etal}}
  • {{cite journal | vauthors=Fukasawa K, Fukasawa KM, Iwamoto H |title=The HELLGH motif of rat liver dipeptidyl peptidase III is involved in zinc coordination and the catalytic activity of the enzyme |journal=Biochemistry |volume=38 |issue= 26 |pages= 8299–303 |year= 1999 |pmid= 10387075 |doi= 10.1021/bi9904959 |display-authors=etal}}
  • {{cite journal | vauthors=Hashimoto J, Yamamoto Y, Kurosawa H |title=Identification of dipeptidyl peptidase III in human neutrophils |journal=Biochem. Biophys. Res. Commun. |volume=273 |issue= 2 |pages= 393–7 |year= 2000 |pmid= 10873616 |doi= 10.1006/bbrc.2000.2827 |display-authors=etal}}
  • {{cite journal | vauthors=Abramić M, Schleuder D, Dolovcak L |title=Human and rat dipeptidyl peptidase III: biochemical and mass spectrometric arguments for similarities and differences |journal=Biol. Chem. |volume=381 |issue= 12 |pages= 1233–43 |year= 2001 |pmid= 11209758 |doi=10.1515/BC.2000.151 |display-authors=etal}}
  • {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
{{refend}}

External links

  • {{UCSC genome browser|DPP3}}
  • {{UCSC gene details|DPP3}}
{{protein-stub}}
随便看

　

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。

　

Copyright © 2023 OENC.NET All Rights Reserved
京ICP备2021023879号 更新时间：2024/11/13 14:46:37