“DPP7”的意思、由来-开放百科全书

The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH.^[3]

References

1. ^{{cite journal | vauthors = Chiravuri M, Schmitz T, Yardley K, Underwood R, Dayal Y, Huber BT | title = A novel apoptotic pathway in quiescent lymphocytes identified by inhibition of a post-proline cleaving aminodipeptidase: a candidate target protease, quiescent cell proline dipeptidase | journal = J Immunol | volume = 163 | issue = 6 | pages = 3092–9 |date=Oct 1999 | pmid = 10477574 | pmc = | doi = }}
2. ^{{cite journal | vauthors = Fukasawa KM, Fukasawa K, Higaki K, Shiina N, Ohno M, Ito S, Otogoto J, Ota N | title = Cloning and functional expression of rat kidney dipeptidyl peptidase II | journal = Biochem J | volume = 353 | issue = Pt 2 | pages = 283–90 |date=Jan 2001 | pmid = 11139392 | pmc = 1221570 | doi =10.1042/0264-6021:3530283 }}
3. ^¹{{cite web | title = Entrez Gene: DPP7 dipeptidyl-peptidase 7| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29952| accessdate = }}

Further reading

{{cite journal | vauthors=Fornas E, Mayordomo F, Renau-Piqueras J, Alborch E |title=Effect of cholesterol and its autooxidation derivatives on endocytosis and dipeptidyl peptidases of aortic endothelial cells |journal=Histol. Histopathol. |volume=7 |issue= 2 |pages= 163–8 |year= 1992 |pmid= 1515698 |doi= }}

{{cite journal | vauthors=Roberts VJ, Gorenstein C |title=The effect of antimitotic agents on the intraneuronal distribution of lysosomes |journal=Brain Res. |volume=521 |issue= 1–2 |pages= 62–72 |year= 1990 |pmid= 2207678 |doi=10.1016/0006-8993(90)91525-L }}

{{cite journal | vauthors=Andersen KJ, McDonald JK |title=Lysosomal heterogeneity of dipeptidyl peptidase II active on collagen-related peptides |journal=Ren. Physiol. Biochem. |volume=12 |issue= 1 |pages= 32–40 |year= 1989 |pmid= 2727382 |doi= 10.1159/000173177}}

{{cite journal | author=Demuth HU |title=Design of (omega-N-(O-acyl)hydroxy amid) aminodicarboxylic acid pyrrolidides as potent inhibitors of proline-specific peptidases |journal=FEBS Lett. |volume=320 |issue= 1 |pages= 23–7 |year= 1993 |pmid= 8096464 |doi=10.1016/0014-5793(93)81649-K |name-list-format=vanc| author2=Schlenzig D | author3=Schierhorn A | display-authors=3 | last4=Grosche | first4=G | last5=Chapotchartier | first5=M | last6=Gripon | first6=J }}

{{cite journal | author=Underwood R |title=Sequence, purification, and cloning of an intracellular serine protease, quiescent cell proline dipeptidase |journal=J. Biol. Chem. |volume=274 |issue= 48 |pages= 34053–8 |year= 1999 |pmid= 10567372 |doi=10.1074/jbc.274.48.34053 |name-list-format=vanc| author2=Chiravuri M | author3=Lee H | display-authors=3 | last4=Schmitz | first4=T | last5=Kabcenell | first5=AK | last6=Yardley | first6=K | last7=Huber | first7=BT }}

{{cite journal | author=Chiravuri M |title=Vesicular localization and characterization of a novel post-proline-cleaving aminodipeptidase, quiescent cell proline dipeptidase |journal=J. Immunol. |volume=165 |issue= 10 |pages= 5695–702 |year= 2000 |pmid= 11067927 |doi= 10.4049/jimmunol.165.10.5695|name-list-format=vanc| author2=Agarraberes F | author3=Mathieu SL | display-authors=3 | last4=Lee | first4=H | last5=Huber | first5=BT }}

{{cite journal | author=Araki H |title=Purification, molecular cloning, and immunohistochemical localization of dipeptidyl peptidase II from the rat kidney and its identity with quiescent cell proline dipeptidase |journal=J. Biochem. |volume=129 |issue= 2 |pages= 279–88 |year= 2001 |pmid= 11173530 |doi= 10.1093/oxfordjournals.jbchem.a002855|name-list-format=vanc| author2=Li Y | author3=Yamamoto Y | display-authors=3 | last4=Haneda | first4=M | last5=Nishi | first5=K | last6=Kikkawa | first6=R | last7=Ohkubo | first7=I }}

{{cite journal | author=Zhan H |title=Peptidases play an important role in cataractogenesis: an immunohistochemical study on lenses derived from Shumiya cataract rats |journal=Histochem. J. |volume=33 |issue= 9–10 |pages= 511–21 |year= 2002 |pmid= 12005022 |doi=10.1023/A:1014943522613 |name-list-format=vanc| author2=Yamamoto Y | author3=Shumiya S | display-authors=3 | last4=Kunimatsu | first4=Mitoshi | last5=Nishi | first5=Katsuji | last6=Ohkubo | first6=Iwao | last7=Kani | first7=Kazutaka }}

{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}

{{cite journal | author=Leiting B |title=Catalytic properties and inhibition of proline-specific dipeptidyl peptidases II, IV and VII |journal=Biochem. J. |volume=371 |issue= Pt 2 |pages= 525–32 |year= 2003 |pmid= 12529175 |doi= 10.1042/BJ20021643 | pmc=1223300 |name-list-format=vanc| author2=Pryor KD | author3=Wu JK | display-authors=3 | last4=Marsilio | first4=Frank | last5=Patel | first5=Reshma A. | last6=Craik | first6=Charles S. | last7=Ellman | first7=Jonathan A. | last8=Cummings | first8=Richard T. | last9=Thornberry | first9=Nancy A. }}

{{cite journal | vauthors=Lehner B, Sanderson CM |title=A Protein Interaction Framework for Human mRNA Degradation |journal=Genome Res. |volume=14 |issue= 7 |pages= 1315–23 |year= 2004 |pmid= 15231747 |doi= 10.1101/gr.2122004 | pmc=442147 }}

{{cite journal | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |name-list-format=vanc| author2=Wagner L | author3=Feingold EA | display-authors=3 | last4=Shenmen | first4=CM | last5=Grouse | first5=LH | last6=Schuler | first6=G | last7=Klein | first7=SL | last8=Old | first8=S | last9=Rasooly | first9=R }}