| 词条 | Drug-induced pigmentation | ||||||||||||||||
| 释义 |
Drug induced pigmentation may take on many different appearances, one of the most common being a change in the color, or pigmentation, of the skin. Clinical presentation
CauseDrug-induced pigmentation of the skin may occur as a consequence of drug administration, and the mechanism may be postinflammatory hyperpigmentation in some cases, but frequently is related to actual deposition of the offending drug in the skin.[1]{{rp|125–6}}The incidence of this change varies, and depends on the type of medication involved. Some of the most common drugs involved are NSAIDs, antimalarials, psychotropic drugs, Amiodarone, cytotoxic drugs, tetracyclines, and heavy metals such as silver and gold (which must be ingested, not just worn).[2] PathophysiologyThere are 4 possible mechanisms to how this change may occur:[2]
See also
References1. ^James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. {{ISBN|0-7216-2921-0}}. 2. ^1 2 Dereure, O. (2001). Drug-Induced Skin Pigmentation: Epidemiology, Diagnosis and Treatment. American Journal of Clinical Dermotology, 2(4), 253-262. External links{{Medical resources| ICD10 = | ICD9 = | ICDO = | OMIM = | DiseasesDB = | MedlinePlus = | eMedicineSubj = article | eMedicineTopic = 1069686 | MeSH = | GeneReviewsNBK = | GeneReviewsName = | Orphanet = }}{{Pigmentation disorders}}{{Cutaneous-condition-stub}} 2 : Drug eruptions|Drug-induced diseases |
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