| 释义 |
- Function
- Interactions
- References
- Further reading
{{Infobox_gene}}DSN1, MIND kinetochore complex component, homolog (S. cerevisiae), also known as DSN1 or MIS13, is a protein which in humans encoded by the DSN1 gene.[1][2]FunctionDSN1 along with MIS12, DC8, PMF1, CBX5, ZWINT is a component of the kinetochore-associated multiprotein complex which is required for correct chromosome alignment during the metaphase of cell mitosis.[2][3] InteractionsDSN1 has been shown to interact with NSL1[4] and MIS12.[2][5] References1. ^{{cite web | title = Entrez Gene: DSN1 DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79980| accessdate = }}
2. ^1 2 {{cite journal | vauthors = Obuse C, Iwasaki O, Kiyomitsu T, Goshima G, Toyoda Y, Yanagida M | title = A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1 | journal = Nat. Cell Biol. | volume = 6 | issue = 11 | pages = 1135–41 |date=November 2004 | pmid = 15502821 | doi = 10.1038/ncb1187 | url = }}
3. ^{{cite journal | vauthors = Yang Y, Wu F, Ward T, Yan F, Wu Q, Wang Z, McGlothen T, Peng W, You T, Sun M, Cui T, Hu R, Dou Z, Zhu J, Xie W, Rao Z, Ding X, Yao X | title = Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore | journal = J. Biol. Chem. | volume = 283 | issue = 39 | pages = 26726–36 |date=September 2008 | pmid = 18640974 | doi = 10.1074/jbc.M804207200 | url = | pmc = 2546542 }}
4. ^{{cite journal |last=Obuse |first=Chikashi |author2=Iwasaki Osamu |author3=Kiyomitsu Tomomi |author4=Goshima Gohta |author5=Toyoda Yusuke |author6=Yanagida Mitsuhiro |date=Nov 2004 |title=A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1 |journal=Nat. Cell Biol. |volume=6 |issue=11 |pages=1135–41 |publisher= |location = England| issn = 1465-7392| pmid = 15502821 |doi = 10.1038/ncb1187 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = }}
5. ^{{cite journal |last=Cheeseman |first=Iain M |author2=Niessen Sherry |author3=Anderson Scott |author4=Hyndman Francie |author5=Yates John R |author6=Oegema Karen |author7=Desai Arshad |date=Sep 2004 |title=A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension |journal=Genes Dev. |volume=18 |issue=18 |pages=2255–68 |publisher= |location = United States| issn = 0890-9369| pmid = 15371340 |doi = 10.1101/gad.1234104 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |pmc=517519 }}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Olsen JV, Blagoev B, Gnad F |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |display-authors=etal}}
- {{cite journal | vauthors=Kline SL, Cheeseman IM, Hori T |title=The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. |journal=J. Cell Biol. |volume=173 |issue= 1 |pages= 9–17 |year= 2006 |pmid= 16585270 |doi= 10.1083/jcb.200509158 | pmc=2063780 |display-authors=etal}}
- {{cite journal | vauthors=Nousiainen M, Silljé HH, Sauer G |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391–6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103 | pmc=1459365 |display-authors=etal|bibcode=2006PNAS..103.5391N }}
- {{cite journal | vauthors=Obuse C, Iwasaki O, Kiyomitsu T |title=A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. |journal=Nat. Cell Biol. |volume=6 |issue= 11 |pages= 1135–41 |year= 2004 |pmid= 15502821 |doi= 10.1038/ncb1187 |display-authors=etal}}
- {{cite journal | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
- {{cite journal | vauthors=Cheeseman IM, Niessen S, Anderson S |title=A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. |journal=Genes Dev. |volume=18 |issue= 18 |pages= 2255–68 |year= 2004 |pmid= 15371340 |doi= 10.1101/gad.1234104 | pmc=517519 |display-authors=etal}}
- {{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
- {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal|bibcode=2002PNAS...9916899M }}
- {{cite journal | vauthors=Deloukas P, Matthews LH, Ashurst J |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a |display-authors=etal|bibcode=2001Natur.414..865D }}
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