DTSA may refer to:

• Defense Technology Security Administration, see Assistant Secretary of Defense for Global Strategic Affairs
• Defend Trade Secrets Act, a United States federal law relating to trade secrets

• Charles Frederick Schomberg
• Charles Frederick Scott
• Charles Frederick Townshend, 2nd Baron Bayning
• Charles Frederick Wright
• Charles Frederic Moberly Bell
• Charles-Frederic Reinhard
• Charles Fredrick Wiesenthal
• Charles Freeman
• Charles Freer
• Charles Freer Andrews
• Charles Fremont Cochran
• Charles Fremont Dight
• Charles French (entomologist)
• Charles Frend
• Charles Freshfield
• Charles Friant
• Charles Friedek
• Charles Fries (producer)
• Charles F. Ritchel
• Charles Fritts
• Charles Frodsham
• Charles Frosst
• Charles-Frédéric, comte Reinhard
• Charles Frédéric Dubois
• Charles Frédéric Petit