| 词条 | Elastofibroma dorsi |
| 释义 |
| name = Elastofibroma dorsi | synonyms = | image = Elastofibroma dorsi - 53jw - CT nativ ax und cor - 001 - Annotation.jpg | alt = | caption = Bilateral elastofibroma dorsi in native computed tomography: left image axial in prone position (for biopsy), right image oblique coronal view. | pronounce = | field = | symptoms = | complications = | onset = | duration = | types = | causes = | risks = | diagnosis = | differential = | prevention = | treatment = | medication = | prognosis = | frequency = | deaths = }}Elastofibroma, also called elastofibroma dorsi, is an ill-defined fibroelastic tumor-like condition made up of enlarged and irregular elastic fibers.[1][2] Signs and SymptomsPatient will present with a slow growing, deep-seated, firm mass, often presenting bilaterally. There may be pain or tenderness, but this is rare.[1][2][5] CauseThere are several theories about origin:
DiagnosisBy computed tomography, there is a poorly circumscribed, heterogeneous soft tissue mass, with a signal intensity similar to skeletal muscle. The fact that the lesion may be bilateral, helps eliminate a sarcoma from further consideration.[4] At US, elastofibromas are depicted deep to the musculature as a multilayered pattern of hypoechoic linear areas of fat deposition intermixed with echogenic fibroelastic tissue.[5] The mass often protrudes from the subscapular region upon shoulder abduction, allowing better delineation of the finding.[6] Pathology findingsIn general, the tumor is an ill defined, nonencapsulated, rubbery, and firm, white lesion with interspersed fat. The tumors can be quite large (up to 20 cm), although most are around 5 cm.[3] By microscopie view, there is an admixture of heavy dense bands of collagenous tissue dissected by fat and abnormal elastic fibers. The elastic fibers are often quite large and are easily identified. The elastic fibers are coarse, thick, and darkly eosinophilic, often fragmented into globules, creating a "string of pearls" or "pipe cleaner" appearance. Because of degeneration, the elastic fibers will appear as globules with a serrated or "prickled" edge.[3] HistochemistryDifferential diagnosesGiven the anatomic site, a spindle cell lipoma, nuchal-type fibroma and fibromatosis colli are all included in the differential diagnosis.[8] ManagementSimple excision is the treatment of choice, although given the large size, bleeding into the space can be a potential complication. Isolated recurrences may be seen, but there is no malignant potential.[2][3][9] EpidemiologyThis is a very rare phenomenon (< 0.001% of soft tissue tumors), usually presenting in elderly patients (>50 years of age), and more commonly in women than men (5:1). There is an increased frequency in Okinawa, Japan, but this may be a reporting bias. The tumor develops very specifically in the subscapular or infrascapular area, deep to the muscle, sometimes even attached to periosteum of ribs. It is usually between the shoulder blade and the lower neck, with rare tumors reported in the chest wall.[1][2][3] See also
References1. ^1 2 {{Cite journal | last1 = Chandrasekar | first1 = C. R. | last2 = Grimer | first2 = R. J. | last3 = Carter | first3 = S. R. | last4 = Tillman | first4 = R. M. | last5 = Abudu | first5 = A. | last6 = Davies | first6 = A. M. | last7 = Sumathi | first7 = V. P. | title = Elastofibroma Dorsi: An Uncommon Benign Pseudotumour | doi = 10.1155/2008/756565 | journal = Sarcoma | volume = 2008 | pages = 1 | year = 2008 | pmid = 18382611 | pmc =2276598 }} 2. ^1 2 3 {{Cite journal | last1 = Briccoli | first1 = A. | last2 = Casadei | first2 = R. | last3 = Di Renzo | first3 = M. | last4 = Favale | first4 = L. | last5 = Bacchini | first5 = P. | last6 = Bertoni | first6 = F. | title = Elastofibroma dorsi | journal = Surgery Today | volume = 30 | issue = 2 | pages = 147–152 | year = 2000 | pmid = 10664338 | doi=10.1007/pl00010063}} 3. ^1 2 3 4 5 {{Cite journal | last1 = Mortman | first1 = K. D. | last2 = Hochheiser | first2 = G. M. | last3 = Giblin | first3 = E. M. | last4 = Manon-Matos | first4 = Y. | last5 = Frankel | first5 = K. M. | title = Elastofibroma Dorsi: Clinicopathologic Review of 6 Cases | doi = 10.1016/j.athoracsur.2006.11.050 | journal = The Annals of Thoracic Surgery | volume = 83 | issue = 5 | pages = 1894–1897 | year = 2007 | pmid = 17462431 | pmc = }} 4. ^{{Cite journal | last1 = Ochsner | first1 = J. E. | last2 = Sewall | first2 = S. A. | last3 = Brooks | first3 = G. N. | last4 = Agni | first4 = R. | title = Best Cases from the AFIP: Elastofibroma Dorsi | doi = 10.1148/rg.266055184 | journal = Radiographics | volume = 26 | issue = 6 | pages = 1873–1876 | year = 2006 | pmid = 17102057 | pmc = }} 5. ^Ochsner JE, Sewall SA, Brooks GN, Agni R. Best cases from the AFIP: Elastofibroma dorsi. Radiographics 2006; 26: 1873-6. 6. ^Arend CF. Ultrasound of the Shoulder. Master Medical Books, 2013. Free section on elastofibroma dorsi as a cause of snapping scapula available at ShoulderUS.com 7. ^{{Cite journal | last1 = Nakamura | first1 = Y. | last2 = Ohta | first2 = Y. | last3 = Itoh | first3 = S. | last4 = Haratake | first4 = A. | last5 = Nakano | first5 = Y. | last6 = Umeda | first6 = A. | last7 = Shima | first7 = H. | last8 = Tomoda | first8 = N. | title = Elastofibroma dorsi. Cytologic, histologic, immunohistochemical and ultrastructural studies | journal = Acta Cytologica | volume = 36 | issue = 4 | pages = 559–562 | year = 1992 | pmid = 1636353}} 8. ^{{Cite journal | last1 = Schafmayer | first1 = C. | last2 = Kahlke | first2 = V. | last3 = Leuschner | first3 = I. | last4 = Pai | first4 = M. | last5 = Tepel | first5 = J. | title = Elastofibroma Dorsi as Differential Diagnosis in Tumors of the Thoracic Wall | doi = 10.1016/j.athoracsur.2005.10.049 | journal = The Annals of Thoracic Surgery | volume = 82 | issue = 4 | pages = 1501–1504 | year = 2006 | pmid = 16996964 | pmc = }} 9. ^{{Cite journal | last1 = Parratt | first1 = M. T. R. | last2 = Donaldson | first2 = J. R. | last3 = Flanagan | first3 = A. M. | last4 = Saifuddin | first4 = A. | last5 = Pollock | first5 = R. C. | last6 = Skinner | first6 = J. A. | last7 = Cannon | first7 = S. R. | last8 = Briggs | first8 = T. W. R. | doi = 10.1302/0301-620X.92B2.22927 | title = Elastofibroma dorsi: Management, outcome and review of the literature | journal = Journal of Bone and Joint Surgery. British Volume | volume = 92-B | issue = 2 | pages = 262–266 | year = 2010 | pmid = 20130320 | pmc = }} Further reading{{cite book |author1=Lester D. R. Thompson |author2=Bruce M Wenig |title=Diagnostic Pathology: Head and Neck: Published by Amirsys |publisher=Lippincott Williams & Wilkins |location=Hagerstown, MD |year=2011 |pages=8:30–31 |isbn=1-931884-61-7 |oclc= |doi= |accessdate=}}External links{{Medical resources| ICD10 = | ICD9 = 215.9 | ICDO = | OMIM = | DiseasesDB = | MedlinePlus = | eMedicineSubj = | eMedicineTopic = | MeSH = | GeneReviewsNBK = | GeneReviewsName = | Orphanet = 228243 }} 1 : Dermal and subcutaneous growths |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。