| 词条 | ELMO3 |
| 释义 |
| Name = engulfment and cell motility 3 | caption = | image = | width = | HGNCid = 17289 | Symbol = ELMO3 | AltSymbols = CED12, FLJ13824 | EntrezGene = 79767 | OMIM = 606422 | RefSeq = NM_024712 | UniProt = Q96BJ8 | PDB = | ECnumber = | Chromosome = 16 | Arm = q | Band = 22.1 | LocusSupplementaryData = }}Engulfment and cell motility 3, also known as ELMO3, is a human gene.[1][2] The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 (DOCK1) protein to promote phagocytosis and effect cell shape changes.[1] References1. ^1 {{cite web | title = Entrez Gene: ELMO3 engulfment and cell motility 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79767 | accessdate = }} 2. ^{{cite journal | vauthors = Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS | title = CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration | journal = Cell | volume = 107 | issue = 1 | pages = 27–41 |date=October 2001 | pmid = 11595183 | doi = 10.1016/S0092-8674(01)00520-7 | url = }} External links
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