释义 |
- Interactions
- References
- Further reading
{{Infobox_gene}}Protein enabled homolog is a protein that in humans is encoded by the ENAH gene.[1][2]InteractionsENAH (gene) has been shown to interact with ABI1[3] and ZYX.[3][4] References1. ^{{cite journal |vauthors=Sazuka T, Tomooka Y, Kathju S, Ikawa Y, Noda M, Kumar S | title = Identification of a developmentally regulated gene in the mouse central nervous system which encodes a novel proline rich protein | journal = Biochim Biophys Acta | volume = 1132 | issue = 3 | pages = 240–8 |date=December 1992 | pmid = 1420303 | pmc = | doi = 10.1016/0167-4781(92)90156-t}} 2. ^{{cite web | title = Entrez Gene: ENAH enabled homolog (Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55740| accessdate = }} 3. ^1 {{cite journal |vauthors=Tani K, Sato S, Sukezane T, Kojima H, Hirose H, Hanafusa H, Shishido T | title = Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase | journal = J. Biol. Chem. | volume = 278 | issue = 24 | pages = 21685–92 | year = 2003 | pmid = 12672821 | doi = 10.1074/jbc.M301447200}} 4. ^{{cite journal |vauthors=Drees B, Friederich E, Fradelizi J, Louvard D, Beckerle MC, Golsteyn RM | title = Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins | journal = J. Biol. Chem. | volume = 275 | issue = 29 | pages = 22503–11 | year = 2000 | pmid = 10801818 | doi = 10.1074/jbc.M001698200}}
Further reading{{refbegin | 2}}- {{cite journal |vauthors=Niebuhr K, Ebel F, Frank R |title=A novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family. |journal=EMBO J. |volume=16 |issue= 17 |pages= 5433–44 |year= 1997 |pmid= 9312002 |doi= 10.1093/emboj/16.17.5433 |pmc=1170174|display-authors=etal}}
- {{cite journal |vauthors=Ermekova KS, Zambrano N, Linn H |title=The WW domain of neural protein FE65 interacts with proline-rich motifs in Mena, the mammalian homolog of Drosophila enabled. |journal=J. Biol. Chem. |volume=272 |issue= 52 |pages= 32869–77 |year= 1998 |pmid= 9407065 |doi=10.1074/jbc.272.52.32869 |display-authors=etal}}
- {{cite journal |vauthors=Mammoto A, Sasaki T, Asakura T |title=Interactions of drebrin and gephyrin with profilin. |journal=Biochem. Biophys. Res. Commun. |volume=243 |issue= 1 |pages= 86–9 |year= 1998 |pmid= 9473484 |doi= 10.1006/bbrc.1997.8068 |display-authors=etal}}
- {{cite journal |vauthors=Geese M, Schlüter K, Rothkegel M |title=Accumulation of profilin II at the surface of Listeria is concomitant with the onset of motility and correlates with bacterial speed. |journal=J. Cell Sci. |volume=113 |issue= 8|pages= 1415–26 |year= 2000 |pmid= 10725224 |doi= |display-authors=etal}}
- {{cite journal |vauthors=Krause M, Sechi AS, Konradt M |title=Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton. |journal=J. Cell Biol. |volume=149 |issue= 1 |pages= 181–94 |year= 2000 |pmid= 10747096 |doi=10.1083/jcb.149.1.181 |pmc=2175102|display-authors=etal}}
- {{cite journal |vauthors=Drees B, Friederich E, Fradelizi J |title=Characterization of the interaction between zyxin and members of the Ena/vasodilator-stimulated phosphoprotein family of proteins. |journal=J. Biol. Chem. |volume=275 |issue= 29 |pages= 22503–11 |year= 2000 |pmid= 10801818 |doi= 10.1074/jbc.M001698200 |display-authors=etal}}
- {{cite journal |vauthors=Krugmann S, Jordens I, Gevaert K |title=Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex. |journal=Curr. Biol. |volume=11 |issue= 21 |pages= 1645–55 |year= 2002 |pmid= 11696321 |doi=10.1016/S0960-9822(01)00506-1 |display-authors=etal}}
- {{cite journal |vauthors=Coutts AS, MacKenzie E, Griffith E, Black DM |title=TES is a novel focal adhesion protein with a role in cell spreading. |journal=J. Cell Sci. |volume=116 |issue= Pt 5 |pages= 897–906 |year= 2003 |pmid= 12571287 |doi=10.1242/jcs.00278 }}
- {{cite journal |vauthors=Tani K, Sato S, Sukezane T |title=Abl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinase. |journal=J. Biol. Chem. |volume=278 |issue= 24 |pages= 21685–92 |year= 2003 |pmid= 12672821 |doi= 10.1074/jbc.M301447200 |display-authors=etal}}
- {{cite journal |vauthors=Garvalov BK, Higgins TE, Sutherland JD |title=The conformational state of Tes regulates its zyxin-dependent recruitment to focal adhesions. |journal=J. Cell Biol. |volume=161 |issue= 1 |pages= 33–9 |year= 2003 |pmid= 12695497 |doi= 10.1083/jcb.200211015 |pmc=2172870|display-authors=etal}}
- {{cite journal |vauthors=Park KW, Morrison CM, Sorensen LK |title=Robo4 is a vascular-specific receptor that inhibits endothelial migration. |journal=Dev. Biol. |volume=261 |issue= 1 |pages= 251–67 |year= 2003 |pmid= 12941633 |doi=10.1016/S0012-1606(03)00258-6 |display-authors=etal}}
- {{cite journal |vauthors=Giesemann T, Schwarz G, Nawrotzki R |title=Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system. |journal=J. Neurosci. |volume=23 |issue= 23 |pages= 8330–9 |year= 2003 |pmid= 12967995 |doi= 10.1523/JNEUROSCI.23-23-08330.2003|display-authors=etal}}
- {{cite journal |vauthors=Salazar MA, Kwiatkowski AV, Pellegrini L |title=Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton. |journal=J. Biol. Chem. |volume=278 |issue= 49 |pages= 49031–43 |year= 2004 |pmid= 14506234 |doi= 10.1074/jbc.M308104200 |display-authors=etal}}
- {{cite journal |vauthors=Stüven T, Hartmann E, Görlich D |title=Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes. |journal=EMBO J. |volume=22 |issue= 21 |pages= 5928–40 |year= 2003 |pmid= 14592989 |doi= 10.1093/emboj/cdg565 |pmc=275422}}
- {{cite journal |vauthors=Di Modugno F, Bronzi G, Scanlan MJ |title=Human Mena protein, a serex-defined antigen overexpressed in breast cancer eliciting both humoral and CD8+ T-cell immune response. |journal=Int. J. Cancer |volume=109 |issue= 6 |pages= 909–18 |year= 2004 |pmid= 15027125 |doi= 10.1002/ijc.20094 |display-authors=etal}}
- {{cite journal |vauthors=Tanoue T, Takeichi M |title=Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact. |journal=J. Cell Biol. |volume=165 |issue= 4 |pages= 517–28 |year= 2004 |pmid= 15148305 |doi= 10.1083/jcb.200403006 |pmc=2172355}}
- {{cite journal |vauthors=Krause M, Leslie JD, Stewart M |title=Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics. |journal=Dev. Cell |volume=7 |issue= 4 |pages= 571–83 |year= 2004 |pmid= 15469845 |doi= 10.1016/j.devcel.2004.07.024 |display-authors=etal}}
{{refend}}{{PDB Gallery|geneid=55740}}{{gene-1-stub}} 1 : EVH1 domain |