“Enamidase”的意思、由来-开放百科全书

词条

Enamidase

释义

References

{{enzyme
| Name = enamidase
| EC_number = 3.5.2.18
| CAS_number =
| IUBMB_EC_number = 3/5/2/18
| GO_code = 0043792
| image =
| width =
| caption =
}}

In enzymology, an enamidase ({{EC number|3.5.2.18}}) is an enzyme that catalyzes the chemical reaction

6-oxo-1,4,5,6-tetrahydronicotinate + 2 H₂O 2-formylglutarate + NH₃

Thus, the two substrates of this enzyme are 6-oxo-1,4,5,6-tetrahydronicotinate and H₂O, whereas its two products are 2-formylglutarate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is 6-oxo-1,4,5,6-tetrahydronicotinate amidohydrolase.

References

{{cite journal | vauthors = Alhapel A, Darley DJ, Wagener N, Eckel E, Elsner N, Pierik AJ | date = 2006 | title = Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 103 | pages = 12341–6 | pmid = 16894175 | doi = 10.1073/pnas.0601635103 | issue = 33 | pmc = 1562527 }}

{{Carbon-nitrogen non-peptide hydrolases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{3.5-enzyme-stub}}

2 : EC 3.5.2|Enzymes of unknown structure

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