Enniskillen may refer to:

• The town of Enniskillen in Northern Ireland
• Enniskillen (Northern Ireland Parliament constituency)
• Enniskillen (UK Parliament constituency)
• Enniskillen, County Tyrone, a downland in County Tyrone, Northern Ireland
• Wirral-Enniskillen - Local Service District in New Brunswick Canada
• Enniskillen, Ontario, a township in Ontario, Canada
• Enniskillen No. 3, Saskatchewan, Canada
• Enniskillen Castle

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