| 词条 | Eperezolid |
| 释义 |
| Verifiedfields = changed | verifiedrevid = 406013269 | IUPAC_name = (S)-N-[[3-[3-Fluoro-4-[4-(2-hydroxyacetyl)piperazin- 1-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide | image = Eperezolid.png | alt = Skeletal formula of eperezolid | width = 260 | image2 = Eperezolid 3D spacefill.png | alt2 = Space-filling model of the eperezolid molecule | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 165800-04-4 | ATC_prefix = none | ATC_suffix = | PubChem = 73214 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | UNII_Ref = {{fdacite|changed|FDA}} | UNII = C460ZSU1OW | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D04017 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 47955 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 65969 | C=18 | H=23 | F=1 | N=4 | O=5 | molecular_weight = 394.40 | smiles = CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCN(CC3)C(=O)CO)F | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C18H23FN4O5/c1-12(25)20-9-14-10-23(18(27)28-14)13-2-3-16(15(19)8-13)21-4-6-22(7-5-21)17(26)11-24/h2-3,8,14,24H,4-7,9-11H2,1H3,(H,20,25)/t14-/m0/s1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = SIMWTRCFFSTNMG-AWEZNQCLSA-N }} Eperezolid is an oxazolidinone antibiotic. SynthesisSee alsoLinezolidReferences1. ^{{Cite journal | doi = 10.1021/jm9509556| title = Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections| journal = Journal of Medicinal Chemistry| volume = 39| issue = 3| pages = 673–9| year = 1996| last1 = Brickner | first1 = S. J. | last2 = Hutchinson | first2 = D. K. | last3 = Barbachyn | first3 = M. R. | last4 = Manninen | first4 = P. R. | last5 = Ulanowicz | first5 = D. A. | last6 = Garmon | first6 = S. A. | last7 = Grega | first7 = K. C. | last8 = Hendges | first8 = S. K. | last9 = Toops | first9 = D. S. | last10 = Ford | first10 = C. W. | last11 = Zurenko | first11 = G. E. | pmid=8576909}} {{Protein synthesis inhibitor antibiotics}}{{antibiotic-stub}} 5 : Oxazolidinone antibiotics|Acetamides|Fluoroarenes|Piperazines|Alcohols |
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