| 词条 | Epomediol |
| 释义 |
| IUPAC_name = (1s,4r,6R,7S)-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane-6,7-diol | image = Epomediol.svg | alt = Skeletal formula | image2 = Epomediol-3D-balls.png | alt2 = Ball-and-stick model | width2 = 180 | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number = 56084-15-2 | ATC_prefix = A05 | ATC_suffix = BA05 | PubChem = 115056 | ChemSpiderID = 102967 | C=10 | H=18 | O=3 | molecular_weight = 186.248 g/mol | smiles = OC1CC2C(OC1(C)C(O)C2)(C)C | synonyms = 1,3,3-Trimethyl-2-oxabicyclo [2.2.2]octane-6,7-endo,endo-diol }}Epomediol (trade name Clesidren) is a synthetic terpenoid with choleretic effects. It has been used in the symptomatic treatment of itching due to intrahepatic cholestasis of pregnancy.[1][2][3] References1. ^{{cite journal |vauthors=Gonzalez MC, Iglesias J, Tiribelli C |title=Epomediol ameliorates pruritus in patients with intrahepatic cholestasis of pregnancy |journal=J Hepatol |volume=16 |issue=1-2 |pages=241–2 |date=September 1992 |pmid=1484159 |doi= 10.1016/S0168-8278(05)80122-9|url=http://linkinghub.elsevier.com/retrieve/pii/S0168-8278(05)80122-9|display-authors=etal}} {{Bile and liver therapy}}{{gastrointestinal-drug-stub}}2. ^{{cite journal |author=Reyes H |title=The spectrum of liver and gastrointestinal disease seen in cholestasis of pregnancy |journal=Gastroenterol Clin North Am |volume=21 |issue=4 |pages=905–21 |date=December 1992 |pmid=1478743 |doi= |url=}} 3. ^{{cite journal |vauthors=Reyes H, Simon FR |title=Intrahepatic cholestasis of pregnancy: an estrogen-related disease |journal=Semin Liver Dis |volume=13 |issue=3 |pages=289–301 |date=August 1993 |pmid=8235718 |doi= 10.1055/s-2007-1007357|url=}} 1 : Monoterpenes |
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