词条 | Erbulozole |
释义 |
| Watchedfields = changed | verifiedrevid = 443731559 | IUPAC_name = | image = Erbuzole structure.png | width = 200 | tradename = | pregnancy_category = | legal_status = | routes_of_administration = | bioavailability = | metabolism = | excretion = | CAS_number = 124784-31-2 | ATC_suffix = | PubChem = 9934372 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID = 8110000 | synonyms = Erbuzole | C=24 | H=27 | N=3 | O=5 | S=1 | molecular_weight = 469.55g/mol | smiles = CCOC(=O)NC1=CC=C(C=C1)SC[C@H]2CO[C@](O2)(CN3C=CN=C3)C4=CC=C(C=C4)OC | StdInChI = 1S/C24H27N3O5S/c1-3-30-23(28)26-19-6-10-22(11-7-19)33-15-21-14-31-24(32-21,16-27-13-12-25-17-27)18-4-8-20(29-2)9-5-18/h4-13,17,21H,3,14-16H2,1-2H3,(H,26,28)/t21-,24+/m1/s1 | StdInChIKey = KLEPCGBEXOCIGS-QPPBQGQZSA-N }}Erbulozole (R55104) is a congener of the microtubule inhibitor tubulozole. It is undergoing phase I clinical trials as a chemotherapeutic agent.[1] SynthesisReferences1. ^{{Cite journal| last1 = Van Belle| first1 = SJ| last2 = Distelmans| first2 = W| last3 = Vandebroek| first3 = J| last4 = Bruynseels| first4 = J| last5 = Van Ginckel| first5 = R| last6 = Storme| first6 = GA| title = Phase I trial of erbulozole (R55104)| journal = Anticancer Research| volume = 13| issue = 6B| pages = 2389–91| year = 1993| pmid = 8135472}} Other reading
1 : Experimental cancer drugs |
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