“Erythritol kinase”的意思、由来-开放百科全书

词条

Erythritol kinase

释义

Structural studies
References

{{enzyme
| Name = erythritol kinase
| EC_number = 2.7.1.27
| CAS_number = 9030-64-2
| IUBMB_EC_number = 2/7/1/27
| GO_code = 0047878
| image =
| width =
| caption =
}}

In enzymology, an erythritol kinase ({{EC number|2.7.1.27}}) is an enzyme that catalyzes the chemical reaction

ATP + erythritol ADP + D-erythritol 4-phosphate

Thus, the two substrates of this enzyme are ATP and erythritol, whereas its two products are ADP and D-erythritol 4-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:erythritol 4-phosphotransferase. This enzyme is also called erythritol kinase (phosphorylating).

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code {{PDB link|1V5S}}.

References

{{cite journal |vauthors=HOLTEN D, FROMM HJ | date = 1961 | title = Purification and properties of erythritol kinase from Propionibacterium pentosaceum | journal = J. Biol. Chem. | volume = 236 | pages = 2581–4 | pmid = 13908588 }}
{{cite journal |vauthors=HOLTEN D, FROMM HJ | date = 1961 | title = Purification and properties of erythritol kinase from Propionibacterium pentosaceum | journal = J. Biol. Chem. | volume = 236 | pages = 2581–4 | pmid = 13908588 }}

2 : EC 2.7.1|Enzymes of known structure

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