| 词条 | Etafedrine |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 449580400 | IUPAC_name = (1R,2S)-2-[Ethyl(methyl)amino]-1-phenyl-1-propanol | image = Etafedrine.svg | width = 180 | tradename = | pregnancy_category = | legal_status = Withdrawn from market | routes_of_administration = | bioavailability = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 7681-79-0 | ATC_prefix = none | ATC_suffix = | PubChem = 10734 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 2Y6VQU63E8 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 85308 | SMILES = O[C@H](c1ccccc1)[C@@H](N(CC)C)C | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C12H19NO/c1-4-13(3)10(2)12(14)11-8-6-5-7-9-11/h5-10,12,14H,4H2,1-3H3/t10-,12-/m0/s1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = IRVLBORJKFZWMI-JQWIXIFHSA-N | C=12 | H=19 | N=1 | O=1 | molecular_weight = 193.285 g/mol }} Etafedrine (INN) or ethylephedrine is a long-acting bronchodilator and has the brand name Nethaprin. It was previously commercially available as both the free base and as the hydrochloride salt from Sanofi-Aventis (now Sanofi) but is now no longer marketed. PharmacologyUnlike ephedrine and tyramine, etafedrine does not induce the release of epinephrine or norepinephrine and instead acts as a selective β2 adrenoreceptor agonist, thereby mediating its bronchodilator effects.[1] See also
References1. ^{{cite journal | last1 = Lindmar |first1=R|first2= K|first3= U | title = On the mechanism of bronchodilatation by etafedrine | journal = Arzneimittel-Forschung | volume = 35 | issue = 3 | pages = 602–4 | year = 1985 | pmid = 4039586 | doi = | url = | last2 = Löffelholz | last3 = Stieh-Koch }} {{Adrenergics}}{{Phenethylamines}}{{Stimulants}} 4 : Abandoned drugs|Alcohols|Bronchodilators|Substituted amphetamines |
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