“Ethanolamine-phosphate cytidylyltransferase”的意思、由来-开放百科全书

词条

Ethanolamine-phosphate cytidylyltransferase

释义

References

{{enzyme
| Name = ethanolamine-phosphate cytidylyltransferase
| EC_number = 2.7.7.14
| CAS_number = 9026-33-9
| IUBMB_EC_number = 2/7/7/14
| GO_code = 0004306
| image =
| width =
| caption =
}}

In enzymology, an ethanolamine-phosphate cytidylyltransferase ({{EC number|2.7.7.14}}) is an enzyme that catalyzes the chemical reaction

CTP + ethanolamine phosphate diphosphate + CDP-ethanolamine

Thus, the two substrates of this enzyme are CTP and ethanolamine phosphate, whereas its two products are diphosphate and CDP-ethanolamine.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:ethanolamine-phosphate cytidylyltransferase. Other names in common use include phosphorylethanolamine transferase, ET, CTP-phosphoethanolamine cytidylyltransferase, phosphoethanolamine cytidylyltransferase, and ethanolamine phosphate cytidylyltransferase. This enzyme participates in aminophosphonate metabolism and glycerophospholipid metabolism.

References

{{cite journal |vauthors=KENNEDY EP, WEISS SB | date = 1956 | title = The function of cytidine coenzymes in the biosynthesis of phospholipides | journal = J. Biol. Chem. | volume = 222 | pages = 193–214 | pmid = 13366993 | issue = 1 }}
{{cite journal | author = Sundler R | date = 1975 | title = Ethanolaminephosphate cytidylyltransferase. Purification and characterization of the enzyme from rat liver | journal = J. Biol. Chem. | volume = 250 | pages = 8585–90 | pmid = 241749 | issue = 22 }}
{{cite journal |vauthors=Visedo-Gonzalez E, Dixon HB | date = 1989 | title = 2-Aminoethylarsonic acid as an analogue of ethanolamine phosphate Endowment of ethanolamine-phosphate cytidylyltransferase with CTP pyrophosphatase activity | journal = Biochem. J. | volume = 260 | pages = 299–301 | pmid = 2549956 | issue = 1 | pmc = 1138663 }}

2 : EC 2.7.7|Enzymes of unknown structure

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