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词条 Eugeroic
释义

  1. Examples

     Marketed  Discontinued  Never marketed  In Development 

  2. See also

     Categories 

  3. References

{{Infobox drug class
| Name =
| Image = Modafinil.svg
| Alt =
| Caption = The chemical structure of modafinil, the prototypical drug of this class.
| Pronounce =
| Synonyms = wakefulness-promoting agent
wakefulness-promoting drug
| Use = Promote wakefulness and alertness
| ATC_prefix = N06B
| Mode_of_action =
| Mechanism_of_action =
| Biological_target =
| Chemical_class =
| Drugs.com =
| Consumer_Reports =
| medicinenet =
| rxlist =
| MeshID =
}}Eugeroics (originally, "eugrégorique" or "eugregoric"),[1] also known as wakefulness-promoting agents and wakefulness-promoting drugs, are a class of drugs that promote wakefulness and alertness.[2][3] They are used medically for the treatment of certain sleeping disorders, such as excessive daytime sleepiness and narcolepsy.[2][3] They generally have a very low addictive potential.[2][3]

The prototypical eugeroic is modafinil; other drugs in the class include adrafinil and armodafinil. Modafinil and armodafinil have been found to act as selective, weak, atypical dopamine reuptake inhibitors.[2][3] Adrafinil is a prodrug of modafinil and therefore has the same mechanism of action as modafinil.

Examples

Marketed

  • Armodafinil
  • Modafinil

Discontinued

  • Adrafinil

Never marketed

  • CRL-40,940 (also called flumodafinil, bisfluoromodafinil, lauflumide)
  • CRL-40,941
  • Fluorenol

In Development

  • Solriamfetol

See also

  • Stimulant

Categories

{{See also for drug classes defined by psychological effects}}

References

1. ^{{cite journal|last1=Milgram|first1=Norton W.|last2=Callahan|first2=Heather|last3=Siwak|first3=Christina|title=Adrafinil: A Novel Vigilance Promoting Agent|journal=CNS Drug Reviews|volume=5|issue=3|year=2006|pages=193–212|issn=1080-563X|doi=10.1111/j.1527-3458.1999.tb00100.x}}
2. ^{{cite web|title=Provigil: Prescribing information|url=http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020717s037s038lbl.pdf|website=United States Food and Drug Administration|publisher=Cephalon, Inc|accessdate=16 August 2015|date=January 2015}}
3. ^{{cite web|title=Nuvigil: Prescribing information|url=http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/021875s021lbledt.pdf|website=United States Food and Drug Administration|publisher=Cephalon, Inc|accessdate=16 August 2015|date=April 2015}}
{{Stimulants}}

2 : Drug classes defined by psychological effects|Nootropics

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