词条 | Evoxine |
释义 |
| Watchedfields = changed | verifiedrevid = 432325202 | ImageFile = Evoxine.png | ImageAlt = | IUPACName = (±)-1-(4,8-Dimethoxyfuro[2,3-b]quinolin-7-yl)oxy-3-methylbutane-2,3-diol | OtherNames = Haploperine |Section1={{Chembox Identifiers | CASNo = 522-11-2 | PubChem = 73416 | ChEMBL = 1416006 | SMILES = CC(C)(C(COC1=C(C2=C(C=C1)C(=C3C=COC3=N2)OC)OC)O)O | ChemSpiderID = 66130 | InChI = 1/C18H21NO6/c1-18(2,21)13(20)9-25-12-6-5-10-14(16(12)23-4)19-17-11(7-8-24-17)15(10)22-3/h5-8,13,20-21H,9H2,1-4H3 | InChIKey = FGANMDNHTVJAHL-UHFFFAOYAV | StdInChI = 1S/C18H21NO6/c1-18(2,21)13(20)9-25-12-6-5-10-14(16(12)23-4)19-17-11(7-8-24-17)15(10)22-3/h5-8,13,20-21H,9H2,1-4H3 | StdInChIKey = FGANMDNHTVJAHL-UHFFFAOYSA-N}} |Section2={{Chembox Properties | C=18 | H=21 | N=1 | O=6 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} |Section5={{Chembox Pharmacology | ATCCode_prefix = none | AdminRoutes = | Bioavail = | Metabolism = | HalfLife = | ProteinBound = | Excretion = | Legal_status = | Legal_US = | Legal_UK = | Legal_AU = | Legal_CA = | Pregnancy_category = | Pregnancy_AU = | Pregnancy_US = }} }}Evoxine (haploperine) is a furoquinoline alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants including Evodia xanthoxyloides[1] and Teclea gerrardii.[2] References1. ^{{cite journal | doi = 10.1071/CH9540087 | last1 = Eastwood | first1 = FW | last2 = Hughes | first2 = GK | last3 = Ritchie | first3 = E. | year = 1954 | title = Alkaloids of the Australian Rutaceae: Evodia xanthoxyloides F.Muell. IV. The structures of Evoxine and Evoxoidine | url = | journal = Australian Journal of Chemistry | volume = 7 | issue = 1| pages = 87–98 }} {{Hypnotics and sedatives}}{{sedative-stub}}2. ^{{cite journal | last1 = Waffo | first1 = AF | last2 = Coombes | first2 = PH | last3 = Crouch | first3 = NR | last4 = Mulholland | first4 = DA | last5 = El Amin | first5 = SM | last6 = Smith | first6 = PJ | title = Acridone and furoquinoline alkaloids from Teclea gerrardii (Rutaceae: Toddalioideae) of southern Africa. | journal = Phytochemistry | volume = 68 | issue = 5 | pages = 663–7 | year = 2007 | pmid = 17174364 | doi = 10.1016/j.phytochem.2006.10.011 }} 7 : Hypnotics|Phenol ethers|Vicinal diols|Nitrogen heterocycles|Oxygen heterocycles|Alkaloids|Heterocyclic compounds (3 rings) |
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