| 释义 |
- References
- Further reading
- External links
{{Infobox_gene}}FYVE, RhoGEF and PH domain-containing protein 4 is a protein that in humans is encoded by the FGD4 gene.[1][2]References1. ^{{cite journal | vauthors = Ikeda W, Nakanishi H, Takekuni K, Itoh S, Takai Y | title = Identification of splicing variants of Frabin with partly different functions and tissue distribution | journal = Biochem Biophys Res Commun | volume = 286 | issue = 5 | pages = 1066–72 |date=Aug 2001 | pmid = 11527409 | pmc = | doi = 10.1006/bbrc.2001.5481 }}
2. ^{{cite web | title = Entrez Gene: FGD4 FYVE, RhoGEF and PH domain containing 4| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=121512| accessdate = }}
Further reading{{refbegin | 2}}- {{cite journal | vauthors=Obaishi H, Nakanishi H, Mandai K |title=Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinase |journal=J. Biol. Chem. |volume=273 |issue= 30 |pages= 18697–700 |year= 1998 |pmid= 9668039 |doi=10.1074/jbc.273.30.18697 |display-authors=etal}}
- {{cite journal | vauthors=Ikeda W, Nakanishi H, Tanaka Y |title=Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation |journal=Oncogene |volume=20 |issue= 27 |pages= 3457–63 |year= 2001 |pmid= 11429692 |doi= 10.1038/sj.onc.1204463 |display-authors=etal}}
- {{cite journal | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
- {{cite journal | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
- {{cite journal | vauthors=Chen XM, Splinter PL, Tietz PS |title=Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42 |journal=J. Biol. Chem. |volume=279 |issue= 30 |pages= 31671–8 |year= 2004 |pmid= 15133042 |doi= 10.1074/jbc.M401592200 |display-authors=etal}}
- {{cite journal | vauthors=De Sandre-Giovannoli A, Delague V, Hamadouche T |title=Homozygosity mapping of autosomal recessive demyelinating Charcot-Marie-Tooth neuropathy (CMT4H) to a novel locus on chromosome 12p11.21-q13.11 |journal=J. Med. Genet. |volume=42 |issue= 3 |pages= 260–5 |year= 2006 |pmid= 15744041 |doi= 10.1136/jmg.2004.024364 | pmc=1736004 |display-authors=etal}}
- {{cite journal | vauthors=Delague V, Jacquier A, Hamadouche T |title=Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H |journal=Am. J. Hum. Genet. |volume=81 |issue= 1 |pages= 1–16 |year= 2007 |pmid= 17564959 |doi= 10.1086/518428 | pmc=1950914 |display-authors=etal}}
- {{cite journal | vauthors=Stendel C, Roos A, Deconinck T |title=Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4 |journal=Am. J. Hum. Genet. |volume=81 |issue= 1 |pages= 158–64 |year= 2007 |pmid= 17564972 |doi= 10.1086/518770 | pmc=1950925 |display-authors=etal}}
{{refend}}External links- [https://www.ncbi.nlm.nih.gov/books/NBK1468/ GeneReviews/NCBI/NIH/UW entry on Charcot-Marie-Tooth Neuropathy Type 4]
{{GTP-binding protein regulators}}{{gene-12-stub}} |