“FGF14”的意思、由来-开放百科全书

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene.^[3]

References

1. ^{{cite journal |vauthors=Smallwood PM, Munoz-Sanjuan I, Tong P, Macke JP, Hendry SH, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J | title = Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development | journal = Proc Natl Acad Sci U S A | volume = 93 | issue = 18 | pages = 9850–7 |date=Oct 1996 | pmid = 8790420 | pmc = 38518 | doi =10.1073/pnas.93.18.9850 }}
2. ^{{cite journal |vauthors=Wozniak DF, Xiao M, Xu L, Yamada KA, Ornitz DM | title = Impaired spatial learning and defective theta burst induced LTP in mice lacking fibroblast growth factor 14 | journal = Neurobiol Dis | volume = 26 | issue = 1 | pages = 14–26 |date=Mar 2007 | pmid = 17236779 | pmc = 2267915 | doi = 10.1016/j.nbd.2006.11.014 }}
3. ^¹{{cite web | title = Entrez Gene: FGF14 fibroblast growth factor 14| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2259| accessdate = }}

Further reading

{{cite journal | author=Wang Q |title=Ataxia and paroxysmal dyskinesia in mice lacking axonally transported FGF14 |journal=Neuron |volume=35 |issue= 1 |pages= 25–38 |year= 2002 |pmid= 12123606 |doi=10.1016/S0896-6273(02)00744-4 |name-list-format=vanc| author2=Bardgett ME | author3=Wong M | display-authors=3 | last4=Wozniak | first4=David F. | last5=Lou | first5=Junyang | last6=McNeil | first6=Benjamin D. | last7=Chen | first7=Chen | last8=Nardi | first8=Anthony | last9=Reid | first9=David C. }}

{{cite journal | author=Chumakov I |title=Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 21 |pages= 13675–80 |year= 2002 |pmid= 12364586 |doi= 10.1073/pnas.182412499 | pmc=129739 |name-list-format=vanc| author2=Blumenfeld M | author3=Guerassimenko O | display-authors=3 | last4=Cavarec | first4=L | last5=Palicio | first5=M | last6=Abderrahim | first6=H | last7=Bougueleret | first7=L | last8=Barry | first8=C | last9=Tanaka | first9=H }}

{{cite journal | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |name-list-format=vanc| author2=Feingold EA | author3=Grouse LH | display-authors=3 | last4=Derge | first4=JG | last5=Klausner | first5=RD | last6=Collins | first6=FS | last7=Wagner | first7=L | last8=Shenmen | first8=CM | last9=Schuler | first9=GD }}

{{cite journal | author=van Swieten JC |title=A Mutation in the Fibroblast Growth Factor 14 Gene Is Associated with Autosomal Dominant Cerebral Ataxia |journal=Am. J. Hum. Genet. |volume=72 |issue= 1 |pages= 191–9 |year= 2003 |pmid= 12489043 |doi=10.1086/345488 | pmc=378625 |name-list-format=vanc| author2=Brusse E | author3=de Graaf BM | display-authors=3 | last4=Krieger | first4=Elmar | last5=Van De Graaf | first5=Raoul | last6=De Koning | first6=Inge | last7=Maat-Kievit | first7=Anneke | last8=Leegwater | first8=Peter | last9=Dooijes | first9=Dennis }}

{{cite journal | author=Dunham A |title=The DNA sequence and analysis of human chromosome 13 |journal=Nature |volume=428 |issue= 6982 |pages= 522–8 |year= 2004 |pmid= 15057823 |doi= 10.1038/nature02379 | pmc=2665288 |name-list-format=vanc| author2=Matthews LH | author3=Burton J | display-authors=3 | last4=Ashurst | first4=J. L. | last5=Howe | first5=K. L. | last6=Ashcroft | first6=K. J. | last7=Beare | first7=D. M. | last8=Burford | first8=D. C. | last9=Hunt | first9=S. E. }}

{{cite journal |vauthors=Popovici C, Conchonaud F, Birnbaum D, Roubin R |title=Functional phylogeny relates LET-756 to fibroblast growth factor 9 |journal=J. Biol. Chem. |volume=279 |issue= 38 |pages= 40146–52 |year= 2004 |pmid= 15199049 |doi= 10.1074/jbc.M405795200 }}

{{cite journal | author=Stevanin G |title=Mutations in the FGF14 gene are not a major cause of spinocerebellar ataxia in Caucasians |journal=Neurology |volume=63 |issue= 5 |pages= 936 |year= 2005 |pmid= 15365159 |doi= 10.1212/01.wnl.0000137020.30604.1e|name-list-format=vanc| author2=Durr A | author3=Dussert C | display-authors=3 | last4=Penet | first4=C | last5=Brice | first5=A }}

{{cite journal | author=Dalski A |title=Mutation analysis in the fibroblast growth factor 14 gene: frameshift mutation and polymorphisms in patients with inherited ataxias |journal=Eur. J. Hum. Genet. |volume=13 |issue= 1 |pages= 118–20 |year= 2005 |pmid= 15470364 |doi= 10.1038/sj.ejhg.5201286 |name-list-format=vanc| author2=Atici J | author3=Kreuz FR | display-authors=3 | last4=Hellenbroich | first4=Yorck | last5=Schwinger | first5=Eberhard | last6=Zühlke | first6=Christine }}

{{cite journal | author=Lou JY |title=Fibroblast growth factor 14 is an intracellular modulator of voltage-gated sodium channels |journal=J. Physiol. |volume=569 |issue= Pt 1 |pages= 179–93 |year= 2006 |pmid= 16166153 |doi= 10.1113/jphysiol.2005.097220 | pmc=1464207 |name-list-format=vanc| author2=Laezza F | author3=Gerber BR | display-authors=3 | last4=Xiao | first4=M | last5=Yamada | first5=KA | last6=Hartmann | first6=H | last7=Craig | first7=AM | last8=Nerbonne | first8=JM | last9=Ornitz | first9=DM }}

{{cite journal | author=Brusse E |title=Spinocerebellar ataxia associated with a mutation in the fibroblast growth factor 14 gene (SCA27): A new phenotype |journal=Mov. Disord. |volume=21 |issue= 3 |pages= 396–401 |year= 2006 |pmid= 16211615 |doi= 10.1002/mds.20708 |name-list-format=vanc| author2=de Koning I | author3=Maat-Kievit A | display-authors=3 | last4=Oostra | first4=Ben A. | last5=Heutink | first5=Peter | last6=Van Swieten | first6=John C. }}

{{cite journal |vauthors=Zhao Y, Lim SW, Tan EK |title=Genetic analysis of SCA 27 in ataxia and childhood onset postural tremor |journal=Am. J. Med. Genet. B Neuropsychiatr. Genet. |volume=144 |issue= 3 |pages= 395–6 |year= 2007 |pmid= 17221845 |doi= 10.1002/ajmg.b.30472 }}